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Prep1 (pKnox1)-deficiency leads to spontaneous tumor development in mice and accelerates EmuMyc lymphomagenesis: a tumor suppressor role for Prep1.
Longobardi E, Iotti G, Di Rosa P, Mejetta S, Bianchi F, Fernandez-Diaz LC, Micali N, Nuciforo P, Lenti E, Ponzoni M, Doglioni C, Caniatti M, Di Fiore PP, Blasi F. Longobardi E, et al. Mol Oncol. 2010 Apr;4(2):126-34. doi: 10.1016/j.molonc.2010.01.001. Epub 2010 Jan 7. Mol Oncol. 2010. PMID: 20106730 Free PMC article.
The homeodomain transcription factor Prep1 (pKnox1) is required for hematopoietic stem and progenitor cell activity.
Di Rosa P, Villaescusa JC, Longobardi E, Iotti G, Ferretti E, Diaz VM, Miccio A, Ferrari G, Blasi F. Di Rosa P, et al. Among authors: longobardi e. Dev Biol. 2007 Nov 15;311(2):324-34. doi: 10.1016/j.ydbio.2007.08.031. Epub 2007 Aug 24. Dev Biol. 2007. PMID: 17904118 Free article.
Most of the hypomorphic Prep1(i/i) embryos (expressing 3-10% of the Prep1 protein), die between E17.5 and P0, with profound anemia, eye malformations and angiogenic anomalies [Ferretti, E., Villaescusa, J.C., Di Rosa, P., Fernandez-Diaz, L.-C., Longobardi, E. …
Most of the hypomorphic Prep1(i/i) embryos (expressing 3-10% of the Prep1 protein), die between E17.5 and P0, with profound anemia, eye malf …
Induction of HoxB transcription by retinoic acid requires actin polymerization.
Ferrai C, Naum-Onganía G, Longobardi E, Palazzolo M, Disanza A, Diaz VM, Crippa MP, Scita G, Blasi F. Ferrai C, et al. Among authors: longobardi e. Mol Biol Cell. 2009 Aug;20(15):3543-51. doi: 10.1091/mbc.e09-02-0114. Epub 2009 May 28. Mol Biol Cell. 2009. PMID: 19477923 Free PMC article.
60 results