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Atopic eczema and the filaggrin story.
Brown SJ, Irvine AD. Brown SJ, et al. Semin Cutan Med Surg. 2008 Jun;27(2):128-37. doi: 10.1016/j.sder.2008.04.001. Semin Cutan Med Surg. 2008. PMID: 18620134 Review.
Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.
Brown SJ, Relton CL, Liao H, Zhao Y, Sandilands A, McLean WH, Cordell HJ, Reynolds NJ. Brown SJ, et al. Br J Dermatol. 2009 Oct;161(4):884-9. doi: 10.1111/j.1365-2133.2009.09339.x. Epub 2009 Jun 11. Br J Dermatol. 2009. PMID: 19681860 Free PMC article.
Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy.
Brown SJ, Asai Y, Cordell HJ, Campbell LE, Zhao Y, Liao H, Northstone K, Henderson J, Alizadehfar R, Ben-Shoshan M, Morgan K, Roberts G, Masthoff LJ, Pasmans SG, van den Akker PC, Wijmenga C, Hourihane JO, Palmer CN, Lack G, Clarke A, Hull PR, Irvine AD, McLean WH. Brown SJ, et al. J Allergy Clin Immunol. 2011 Mar;127(3):661-7. doi: 10.1016/j.jaci.2011.01.031. J Allergy Clin Immunol. 2011. PMID: 21377035 Free PMC article.
Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations.
Chen H, Common JE, Haines RL, Balakrishnan A, Brown SJ, Goh CS, Cordell HJ, Sandilands A, Campbell LE, Kroboth K, Irvine AD, Goh DL, Tang MB, van Bever HP, Giam YC, McLean WH, Lane EB. Chen H, et al. Among authors: brown sj. Br J Dermatol. 2011 Jul;165(1):106-14. doi: 10.1111/j.1365-2133.2011.10331.x. Br J Dermatol. 2011. PMID: 21428977
836 results