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988 results

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Page 1
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets.
Turner N, Lambros MB, Horlings HM, Pearson A, Sharpe R, Natrajan R, Geyer FC, van Kouwenhove M, Kreike B, Mackay A, Ashworth A, van de Vijver MJ, Reis-Filho JS. Turner N, et al. Among authors: mackay a. Oncogene. 2010 Apr 8;29(14):2013-23. doi: 10.1038/onc.2009.489. Epub 2010 Jan 18. Oncogene. 2010. PMID: 20101236 Free PMC article.
Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours.
Rajan N, Elliott R, Clewes O, Mackay A, Reis-Filho JS, Burn J, Langtry J, Sieber-Blum M, Lord CJ, Ashworth A. Rajan N, et al. Among authors: mackay a. Oncogene. 2011 Oct 13;30(41):4243-60. doi: 10.1038/onc.2011.133. Epub 2011 May 9. Oncogene. 2011. PMID: 21552290 Free PMC article.
Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies.
Shiu KK, Wetterskog D, Mackay A, Natrajan R, Lambros M, Sims D, Bajrami I, Brough R, Frankum J, Sharpe R, Marchio C, Horlings H, Reyal F, van der Vijver M, Turner N, Reis-Filho JS, Lord CJ, Ashworth A. Shiu KK, et al. Among authors: mackay a. Oncogene. 2014 Jan 30;33(5):619-31. doi: 10.1038/onc.2012.625. Epub 2013 Jan 21. Oncogene. 2014. PMID: 23334330 Free article.
FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas.
Reis-Filho JS, Simpson PT, Turner NC, Lambros MB, Jones C, Mackay A, Grigoriadis A, Sarrio D, Savage K, Dexter T, Iravani M, Fenwick K, Weber B, Hardisson D, Schmitt FC, Palacios J, Lakhani SR, Ashworth A. Reis-Filho JS, et al. Among authors: mackay a. Clin Cancer Res. 2006 Nov 15;12(22):6652-62. doi: 10.1158/1078-0432.CCR-06-1164. Clin Cancer Res. 2006. PMID: 17121884
Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines.
Arriola E, Marchio C, Tan DS, Drury SC, Lambros MB, Natrajan R, Rodriguez-Pinilla SM, Mackay A, Tamber N, Fenwick K, Jones C, Dowsett M, Ashworth A, Reis-Filho JS. Arriola E, et al. Among authors: mackay a. Lab Invest. 2008 May;88(5):491-503. doi: 10.1038/labinvest.2008.19. Epub 2008 Mar 10. Lab Invest. 2008. PMID: 18332872 Free article.
Tiling path genomic profiling of grade 3 invasive ductal breast cancers.
Natrajan R, Lambros MB, Rodríguez-Pinilla SM, Moreno-Bueno G, Tan DS, Marchió C, Vatcheva R, Rayter S, Mahler-Araujo B, Fulford LG, Hungermann D, Mackay A, Grigoriadis A, Fenwick K, Tamber N, Hardisson D, Tutt A, Palacios J, Lord CJ, Buerger H, Ashworth A, Reis-Filho JS. Natrajan R, et al. Among authors: mackay a. Clin Cancer Res. 2009 Apr 15;15(8):2711-22. doi: 10.1158/1078-0432.CCR-08-1878. Epub 2009 Mar 24. Clin Cancer Res. 2009. PMID: 19318498 Free article.
An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers.
Natrajan R, Weigelt B, Mackay A, Geyer FC, Grigoriadis A, Tan DS, Jones C, Lord CJ, Vatcheva R, Rodriguez-Pinilla SM, Palacios J, Ashworth A, Reis-Filho JS. Natrajan R, et al. Among authors: mackay a. Breast Cancer Res Treat. 2010 Jun;121(3):575-89. doi: 10.1007/s10549-009-0501-3. Epub 2009 Aug 18. Breast Cancer Res Treat. 2010. PMID: 19688261
988 results