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Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations.
Lauring J, Cosgrove DP, Fontana S, Gustin JP, Konishi H, Abukhdeir AM, Garay JP, Mohseni M, Wang GM, Higgins MJ, Gorkin D, Reis M, Vogelstein B, Polyak K, Cowherd M, Buckhaults PJ, Park BH. Lauring J, et al. Among authors: polyak k. Oncogene. 2010 Apr 22;29(16):2337-45. doi: 10.1038/onc.2009.516. Epub 2010 Jan 25. Oncogene. 2010. PMID: 20101210 Free PMC article.
A model for p53-induced apoptosis.
Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B. Polyak K, et al. Nature. 1997 Sep 18;389(6648):300-5. doi: 10.1038/38525. Nature. 1997. PMID: 9305847
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma.
Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, Markowitz S, Willson JK, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB. Herman JG, et al. Among authors: polyak k. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6870-5. doi: 10.1073/pnas.95.12.6870. Proc Natl Acad Sci U S A. 1998. PMID: 9618505 Free PMC article.
14-3-3sigma is a p53-regulated inhibitor of G2/M progression.
Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, Vogelstein B. Hermeking H, et al. Among authors: polyak k. Mol Cell. 1997 Dec;1(1):3-11. doi: 10.1016/s1097-2765(00)80002-7. Mol Cell. 1997. PMID: 9659898 Free article.
257 results