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Gene expression studies demonstrate that the K-ras/Erk MAP kinase signal transduction pathway and other novel pathways contribute to the pathogenesis of cumene-induced lung tumors.
Wakamatsu N, Collins JB, Parker JS, Tessema M, Clayton NP, Ton TV, Hong HH, Belinsky S, Devereux TR, Sills RC, Lahousse SA. Wakamatsu N, et al. Among authors: clayton np. Toxicol Pathol. 2008 Jul;36(5):743-52. doi: 10.1177/0192623308320801. Epub 2008 Jul 22. Toxicol Pathol. 2008. PMID: 18648096
Useful immunohistochemical markers of tumor differentiation.
Painter JT, Clayton NP, Herbert RA. Painter JT, et al. Among authors: clayton np. Toxicol Pathol. 2010 Jan;38(1):131-41. doi: 10.1177/0192623309356449. Epub 2009 Dec 22. Toxicol Pathol. 2010. PMID: 20028992 Free PMC article.
Analysis of p53 tumor suppressor gene, H-ras protooncogene and proliferating cell nuclear antigen (PCNA) in squamous cell carcinomas of HRA/Skh mice following exposure to 8-methoxypsoralen (8-MOP) and UVA radiation (PUVA therapy).
Lambertini L, Surin K, Ton TV, Clayton N, Dunnick JK, Kim Y, Hong HH, Devereux TR, Sills RC. Lambertini L, et al. Among authors: clayton n. Toxicol Pathol. 2005;33(2):292-9. doi: 10.1080/019262390908380. Toxicol Pathol. 2005. PMID: 15902973
464 results