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Identification of phenylbutyrate-generated metabolites in Huntington disease patients using parallel liquid chromatography/electrochemical array/mass spectrometry and off-line tandem mass spectrometry.
Anal Biochem. 2010 Apr 15;399(2):152-61. doi: 10.1016/j.ab.2010.01.010. Epub 2010 Jan 13.
Anal Biochem. 2010.
PMID: 20074541
Free PMC article.
Metabolite identification using a nanoelectrospray LC-EC-array-MS integrated system.
Schiavo S, Ebbel E, Sharma S, Matson W, Kristal BS, Hersch S, Vouros P.
Schiavo S, et al.
Anal Chem. 2008 Aug 1;80(15):5912-23. doi: 10.1021/ac800507y. Epub 2008 Jun 25.
Anal Chem. 2008.
PMID: 18576668
Free PMC article.
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Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.
Hersch SM, Gevorkian S, Marder K, Moskowitz C, Feigin A, Cox M, Como P, Zimmerman C, Lin M, Zhang L, Ulug AM, Beal MF, Matson W, Bogdanov M, Ebbel E, Zaleta A, Kaneko Y, Jenkins B, Hevelone N, Zhang H, Yu H, Schoenfeld D, Ferrante R, Rosas HD.
Hersch SM, et al.
Neurology. 2006 Jan 24;66(2):250-2. doi: 10.1212/01.wnl.0000194318.74946.b6.
Neurology. 2006.
PMID: 16434666
Clinical Trial.
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