Vajpai N - Search Results

1

Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.

Zhang J, Adrián FJ, Jahnke W, Cowan-Jacob SW, Li AG, Iacob RE, Sim T, Powers J, Dierks C, Sun F, Guo GR, Ding Q, Okram B, Choi Y, Wojciechowski A, Deng X, Liu G, Fendrich G, Strauss A, Vajpai N, Grzesiek S, Tuntland T, Liu Y, Bursulaya B, Azam M, Manley PW, Engen JR, Daley GQ, Warmuth M, Gray NS. Zhang J, et al. Among authors: vajpai n. Nature. 2010 Jan 28;463(7280):501-6. doi: 10.1038/nature08675. Epub 2010 Jan 13. Nature. 2010. PMID: 20072125 Free PMC article.

2

Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib.

Vajpai N, Strauss A, Fendrich G, Cowan-Jacob SW, Manley PW, Grzesiek S, Jahnke W. Vajpai N, et al. J Biol Chem. 2008 Jun 27;283(26):18292-302. doi: 10.1074/jbc.M801337200. Epub 2008 Apr 22. J Biol Chem. 2008. PMID: 18434310 Free article.

3

Backbone NMR resonance assignment of the Abelson kinase domain in complex with imatinib.

Vajpai N, Strauss A, Fendrich G, Cowan-Jacob SW, Manley PW, Jahnke W, Grzesiek S. Vajpai N, et al. Biomol NMR Assign. 2008 Jun;2(1):41-2. doi: 10.1007/s12104-008-9079-7. Epub 2008 Mar 5. Biomol NMR Assign. 2008. PMID: 19636920

4

High-pressure NMR reveals close similarity between cold and alcohol protein denaturation in ubiquitin.

Vajpai N, Nisius L, Wiktor M, Grzesiek S. Vajpai N, et al. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):E368-76. doi: 10.1073/pnas.1212222110. Epub 2013 Jan 2. Proc Natl Acad Sci U S A. 2013. PMID: 23284170 Free PMC article.

5

Kinase in motion: insights into the dynamic nature of p38α by high-pressure NMR spectroscopic studies.

Nielsen G, Jonker HR, Vajpai N, Grzesiek S, Schwalbe H. Nielsen G, et al. Among authors: vajpai n. Chembiochem. 2013 Sep 23;14(14):1799-806. doi: 10.1002/cbic.201300170. Epub 2013 Jul 10. Chembiochem. 2013. PMID: 23843149

6

Side-chain chi(1) conformations in urea-denatured ubiquitin and protein G from (3)J coupling constants and residual dipolar couplings.

Vajpai N, Gentner M, Huang JR, Blackledge M, Grzesiek S. Vajpai N, et al. J Am Chem Soc. 2010 Mar 10;132(9):3196-203. doi: 10.1021/ja910331t. J Am Chem Soc. 2010. PMID: 20155903

7

Residual dipolar couplings measured in unfolded proteins are sensitive to amino-acid-specific geometries as well as local conformational sampling.

Huang JR, Gentner M, Vajpai N, Grzesiek S, Blackledge M. Huang JR, et al. Among authors: vajpai n. Biochem Soc Trans. 2012 Oct;40(5):989-94. doi: 10.1042/BST20120187. Biochem Soc Trans. 2012. PMID: 22988852 Review.

8

Residual dipolar couplings in short peptides reveal systematic conformational preferences of individual amino acids.

Dames SA, Aregger R, Vajpai N, Bernado P, Blackledge M, Grzesiek S. Dames SA, et al. Among authors: vajpai n. J Am Chem Soc. 2006 Oct 18;128(41):13508-14. doi: 10.1021/ja063606h. J Am Chem Soc. 2006. PMID: 17031964

9

Facile backbone structure determination of human membrane proteins by NMR spectroscopy.

Klammt C, Maslennikov I, Bayrhuber M, Eichmann C, Vajpai N, Chiu EJ, Blain KY, Esquivies L, Kwon JH, Balana B, Pieper U, Sali A, Slesinger PA, Kwiatkowski W, Riek R, Choe S. Klammt C, et al. Among authors: vajpai n. Nat Methods. 2012 May 20;9(8):834-9. doi: 10.1038/nmeth.2033. Nat Methods. 2012. PMID: 22609626 Free PMC article.

10

Structural and dynamic insights into the energetics of activation loop rearrangement in FGFR1 kinase.

Klein T, Vajpai N, Phillips JJ, Davies G, Holdgate GA, Phillips C, Tucker JA, Norman RA, Scott AD, Higazi DR, Lowe D, Thompson GS, Breeze AL. Klein T, et al. Among authors: vajpai n. Nat Commun. 2015 Jul 23;6:7877. doi: 10.1038/ncomms8877. Nat Commun. 2015. PMID: 26203596 Free PMC article.

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