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Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini.
Pinlaor P, Kaewpitoon N, Laha T, Sripa B, Kaewkes S, Morales ME, Mann VH, Parriott SK, Suttiprapa S, Robinson MW, To J, Dalton JP, Loukas A, Brindley PJ. Pinlaor P, et al. Among authors: to j. PLoS Negl Trop Dis. 2009;3(3):e398. doi: 10.1371/journal.pntd.0000398. Epub 2009 Mar 24. PLoS Negl Trop Dis. 2009. PMID: 19308250 Free PMC article.
The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages.
Alvarado R, To J, Lund ME, Pinar A, Mansell A, Robinson MW, O'Brien BA, Dalton JP, Donnelly S. Alvarado R, et al. Among authors: to j. FASEB J. 2017 Jan;31(1):85-95. doi: 10.1096/fj.201500093R. Epub 2016 Sep 28. FASEB J. 2017. PMID: 27682204
Helminth parasites secrete molecules that interact with innate immune cells, modulating their activity to ultimately determine the phenotype of differentiated T cells, thus creating an immune environment that is conducive to sustaining chronic infection. ...We propo …
Helminth parasites secrete molecules that interact with innate immune cells, modulating their activity to ultimately determine the ph …
Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation.
Thivierge K, Cotton S, Schaefer DA, Riggs MW, To J, Lund ME, Robinson MW, Dalton JP, Donnelly SM. Thivierge K, et al. Among authors: to j. PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2307. doi: 10.1371/journal.pntd.0002307. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23875042 Free PMC article.
Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs).
Shiels J, Cwiklinski K, Alvarado R, Thivierge K, Cotton S, Gonzales Santana B, To J, Donnelly S, Taggart CC, Weldon S, Dalton JP. Shiels J, et al. Among authors: to j. PLoS Negl Trop Dis. 2020 Jul 9;14(7):e0008470. doi: 10.1371/journal.pntd.0008470. eCollection 2020 Jul. PLoS Negl Trop Dis. 2020. PMID: 32644998 Free PMC article.
Aminopeptidases of malaria parasites: new targets for chemotherapy.
Trenholme KR, Brown CL, Skinner-Adams TS, Stack C, Lowther J, To J, Robinson MW, Donnelly SM, Dalton JP, Gardiner DL. Trenholme KR, et al. Among authors: to j. Infect Disord Drug Targets. 2010 Jun;10(3):217-25. doi: 10.2174/187152610791163363. Infect Disord Drug Targets. 2010. PMID: 20334618 Review.
219 results