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Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.
Kool J, Uren AG, Martins CP, Sie D, de Ridder J, Turner G, van Uitert M, Matentzoglu K, Lagcher W, Krimpenfort P, Gadiot J, Pritchard C, Lenz J, Lund AH, Jonkers J, Rogers J, Adams DJ, Wessels L, Berns A, van Lohuizen M. Kool J, et al. Among authors: wessels l. Cancer Res. 2010 Jan 15;70(2):520-31. doi: 10.1158/0008-5472.CAN-09-2736. Epub 2010 Jan 12. Cancer Res. 2010. PMID: 20068150 Free PMC article.
Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.
Liu X, Holstege H, van der Gulden H, Treur-Mulder M, Zevenhoven J, Velds A, Kerkhoven RM, van Vliet MH, Wessels LF, Peterse JL, Berns A, Jonkers J. Liu X, et al. Among authors: wessels lf. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12111-6. doi: 10.1073/pnas.0702969104. Epub 2007 Jul 11. Proc Natl Acad Sci U S A. 2007. PMID: 17626182 Free PMC article.
Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.
Uren AG, Kool J, Matentzoglu K, de Ridder J, Mattison J, van Uitert M, Lagcher W, Sie D, Tanger E, Cox T, Reinders M, Hubbard TJ, Rogers J, Jonkers J, Wessels L, Adams DJ, van Lohuizen M, Berns A. Uren AG, et al. Among authors: wessels l. Cell. 2008 May 16;133(4):727-41. doi: 10.1016/j.cell.2008.03.021. Cell. 2008. PMID: 18485879 Free PMC article.
Biclustering sparse binary genomic data.
van Uitert M, Meuleman W, Wessels L. van Uitert M, et al. Among authors: wessels l. J Comput Biol. 2008 Dec;15(10):1329-45. doi: 10.1089/cmb.2008.0066. J Comput Biol. 2008. PMID: 19040367
392 results