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Page 1
The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics.
Lucas A, Liu L, Dai E, Bot I, Viswanathan K, Munuswamy-Ramunujam G, Davids JA, Bartee MY, Richardson J, Christov A, Wang H, Macaulay C, Poznansky M, Zhong R, Miller L, Biessen E, Richardson M, Sullivan C, Moyer R, Hatton M, Lomas DA, McFadden G. Lucas A, et al. Among authors: davids ja. Adv Exp Med Biol. 2009;666:132-56. doi: 10.1007/978-1-4419-1601-3_11. Adv Exp Med Biol. 2009. PMID: 20054981 Review.
Viral serpin therapeutics from concept to clinic.
Chen H, Zheng D, Davids J, Bartee MY, Dai E, Liu L, Petrov L, Macaulay C, Thoburn R, Sobel E, Moyer R, McFadden G, Lucas A. Chen H, et al. Methods Enzymol. 2011;499:301-29. doi: 10.1016/B978-0-12-386471-0.00015-8. Methods Enzymol. 2011. PMID: 21683260 Free PMC article. Review.
The serpin solution; targeting thrombotic and thrombolytic serine proteases in inflammation.
Chen H, Davids JA, Zheng D, Bryant M, Bot I, van Berckel TJ, Biessen E, Pepine C, Ryman K, Progulski-Fox A, Kesavalu L, Moyer R, McFadden G, Lucas A. Chen H, et al. Among authors: davids ja. Cardiovasc Hematol Disord Drug Targets. 2013 Aug;13(2):99-110. doi: 10.2174/1871529x11313020003. Cardiovasc Hematol Disord Drug Targets. 2013. PMID: 23987998 Review.
Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection.
Chen H, Zheng D, Abbott J, Liu L, Bartee MY, Long M, Davids J, Williams J, Feldmann H, Strong J, Grau KR, Tibbetts S, Macaulay C, McFadden G, Thoburn R, Lomas DA, Spinale FG, Virgin HW, Lucas A. Chen H, et al. Antimicrob Agents Chemother. 2013 Sep;57(9):4114-27. doi: 10.1128/AAC.02594-12. Epub 2013 Jun 17. Antimicrob Agents Chemother. 2013. PMID: 23774438 Free PMC article.
Serpins for diagnosis and therapy in cancer.
Zheng D, Chen H, Davids J, Bryant M, Lucas A. Zheng D, et al. Cardiovasc Hematol Disord Drug Targets. 2013 Aug;13(2):123-32. doi: 10.2174/1871529x11313020005. Cardiovasc Hematol Disord Drug Targets. 2013. PMID: 23988000 Review.
Viral cross-class serpin inhibits vascular inflammation and T lymphocyte fratricide; a study in rodent models in vivo and human cell lines in vitro.
Viswanathan K, Bot I, Liu L, Dai E, Turner PC, Togonu-Bickersteth B, Richardson J, Davids JA, Williams JM, Bartee MY, Chen H, van Berkel TJ, Biessen EA, Moyer RW, Lucas AR. Viswanathan K, et al. Among authors: davids ja. PLoS One. 2012;7(9):e44694. doi: 10.1371/journal.pone.0044694. Epub 2012 Sep 26. PLoS One. 2012. PMID: 23049756 Free PMC article.
43 results