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The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics.
Lucas A, Liu L, Dai E, Bot I, Viswanathan K, Munuswamy-Ramunujam G, Davids JA, Bartee MY, Richardson J, Christov A, Wang H, Macaulay C, Poznansky M, Zhong R, Miller L, Biessen E, Richardson M, Sullivan C, Moyer R, Hatton M, Lomas DA, McFadden G. Lucas A, et al. Among authors: bot i. Adv Exp Med Biol. 2009;666:132-56. doi: 10.1007/978-1-4419-1601-3_11. Adv Exp Med Biol. 2009. PMID: 20054981 Review.
Time-restricted feeding attenuates hypercholesterolaemia and atherosclerosis development during circadian disturbance in APOE∗3-Leiden.CETP mice.
In Het Panhuis W, Schönke M, Modder M, Tom HE, Lalai RA, Pronk ACM, Streefland TCM, van Kerkhof LWM, Dollé MET, Depuydt MAC, Bot I, Vos WG, Bosmans LA, van Os BW, Lutgens E, Rensen PCN, Kooijman S. In Het Panhuis W, et al. Among authors: bot i. EBioMedicine. 2023 Jul;93:104680. doi: 10.1016/j.ebiom.2023.104680. Epub 2023 Jun 23. EBioMedicine. 2023. PMID: 37356205 Free PMC article.
Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation.
Mulholland M, Depuydt MAC, Jakobsson G, Ljungcrantz I, Grentzmann A, To F, Bengtsson E, Jaensson Gyllenbäck E, Grönberg C, Rattik S, Liberg D, Schiopu A, Björkbacka H, Kuiper J, Bot I, Slütter B, Engelbertsen D. Mulholland M, et al. Among authors: bot i. Cardiovasc Res. 2024 May 7;120(6):581-595. doi: 10.1093/cvr/cvae046. Cardiovasc Res. 2024. PMID: 38563353 Free PMC article.
Single-cell profiling reveals age-associated immunity in atherosclerosis.
Smit V, de Mol J, Schaftenaar FH, Depuydt MAC, Postel RJ, Smeets D, Verheijen FWM, Bogers L, van Duijn J, Verwilligen RAF, Grievink HW, Bernabé Kleijn MNA, van Ingen E, de Jong MJM, Goncalves L, Peeters JAHM, Smeets HJ, Wezel A, Polansky JK, de Winther MPJ, Binder CJ, Tsiantoulas D, Bot I, Kuiper J, Foks AC. Smit V, et al. Among authors: bot i. Cardiovasc Res. 2023 Nov 25;119(15):2508-2521. doi: 10.1093/cvr/cvad099. Cardiovasc Res. 2023. PMID: 37390467 Free PMC article.
Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis.
de Jager SC, Bermúdez B, Bot I, Koenen RR, Bot M, Kavelaars A, de Waard V, Heijnen CJ, Muriana FJ, Weber C, van Berkel TJ, Kuiper J, Lee SJ, Abia R, Biessen EA. de Jager SC, et al. Among authors: bot i, bot m. J Exp Med. 2011 Feb 14;208(2):217-25. doi: 10.1084/jem.20100370. Epub 2011 Jan 17. J Exp Med. 2011. PMID: 21242297 Free PMC article.
Mast cells in atherosclerosis.
Bot I, Biessen EA. Bot I, et al. Thromb Haemost. 2011 Nov;106(5):820-6. doi: 10.1160/TH11-05-0291. Epub 2011 Aug 25. Thromb Haemost. 2011. PMID: 21866302 Review.
139 results