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Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation.
Miraki-Moud F, Anjos-Afonso F, Hodby KA, Griessinger E, Rosignoli G, Lillington D, Jia L, Davies JK, Cavenagh J, Smith M, Oakervee H, Agrawal S, Gribben JG, Bonnet D, Taussig DC. Miraki-Moud F, et al. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13576-81. doi: 10.1073/pnas.1301891110. Epub 2013 Jul 30. Proc Natl Acad Sci U S A. 2013. PMID: 23901108 Free PMC article.
Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo.
Miraki-Moud F, Ghazaly E, Ariza-McNaughton L, Hodby KA, Clear A, Anjos-Afonso F, Liapis K, Grantham M, Sohrabi F, Cavenagh J, Bomalaski JS, Gribben JG, Szlosarek PW, Bonnet D, Taussig DC. Miraki-Moud F, et al. Blood. 2015 Jun 25;125(26):4060-8. doi: 10.1182/blood-2014-10-608133. Epub 2015 Apr 20. Blood. 2015. PMID: 25896651 Free article.
Single cell analysis of clonal architecture in acute myeloid leukaemia.
Potter N, Miraki-Moud F, Ermini L, Titley I, Vijayaraghavan G, Papaemmanuil E, Campbell P, Gribben J, Taussig D, Greaves M. Potter N, et al. Among authors: miraki moud f. Leukemia. 2019 May;33(5):1113-1123. doi: 10.1038/s41375-018-0319-2. Epub 2018 Dec 19. Leukemia. 2019. PMID: 30568172 Free PMC article.
Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function.
Ghazaly EA, Miraki-Moud F, Smith P, Gnanaranjan C, Koniali L, Oke A, Saied MH, Petty R, Matthews J, Stronge R, Joel SP, Young BD, Gribben J, Taussig DC. Ghazaly EA, et al. Among authors: miraki moud f. J Biol Chem. 2020 Apr 17;295(16):5496-5508. doi: 10.1074/jbc.RA119.010467. Epub 2020 Mar 11. J Biol Chem. 2020. PMID: 32161116 Free PMC article.
Quizartinib-resistant FLT3-ITD acute myeloid leukemia cells are sensitive to the FLT3-Aurora kinase inhibitor CCT241736.
Moore AS, Faisal A, Mak GWY, Miraki-Moud F, Bavetsias V, Valenti M, Box G, Hallsworth A, de Haven Brandon A, Xavier CPR, Stronge R, Pearson ADJ, Blagg J, Raynaud FI, Chopra R, Eccles SA, Taussig DC, Linardopoulos S. Moore AS, et al. Among authors: miraki moud f. Blood Adv. 2020 Apr 14;4(7):1478-1491. doi: 10.1182/bloodadvances.2019000986. Blood Adv. 2020. PMID: 32282883 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33509590
31 results