Ashcroft FM - Search Results

1

Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism.

Shimomura K, Flanagan SE, Zadek B, Lethby M, Zubcevic L, Girard CA, Petz O, Mannikko R, Kapoor RR, Hussain K, Skae M, Clayton P, Hattersley A, Ellard S, Ashcroft FM. Shimomura K, et al. Among authors: ashcroft fm. EMBO Mol Med. 2009 Jun;1(3):166-77. doi: 10.1002/emmm.200900018. EMBO Mol Med. 2009. PMID: 20049716 Free PMC article.

2

Identification and electrophysiology of isolated pars compacta neurons from guinea-pig substantia nigra.

Hainsworth AH, Röper J, Kapoor R, Ashcroft FM. Hainsworth AH, et al. Among authors: ashcroft fm. Neuroscience. 1991;43(1):81-93. doi: 10.1016/0306-4522(91)90419-o. Neuroscience. 1991. PMID: 1681461

3

The sulphonylurea receptor confers diazoxide sensitivity on the inwardly rectifying K+ channel Kir6.1 expressed in human embryonic kidney cells.

Ammälä C, Moorhouse A, Ashcroft FM. Ammälä C, et al. Among authors: ashcroft fm. J Physiol. 1996 Aug 1;494 ( Pt 3)(Pt 3):709-14. doi: 10.1113/jphysiol.1996.sp021526. J Physiol. 1996. PMID: 8865068 Free PMC article.

4

Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro.

Sakura H, Wat N, Horton V, Millns H, Turner RC, Ashcroft FM. Sakura H, et al. Among authors: ashcroft fm. Diabetologia. 1996 Oct;39(10):1233-6. doi: 10.1007/BF02658512. Diabetologia. 1996. PMID: 8897013

5

Mechanisms of the glycaemic effects of sulfonylureas.

Ashcroft FM. Ashcroft FM. Horm Metab Res. 1996 Sep;28(9):456-63. doi: 10.1055/s-2007-979837. Horm Metab Res. 1996. PMID: 8911983 Review.

6

The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide.

Gribble FM, Tucker SJ, Ashcroft FM. Gribble FM, et al. Among authors: ashcroft fm. EMBO J. 1997 Mar 17;16(6):1145-52. doi: 10.1093/emboj/16.6.1145. EMBO J. 1997. PMID: 9135131 Free PMC article.

7

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor.

Tucker SJ, Gribble FM, Zhao C, Trapp S, Ashcroft FM. Tucker SJ, et al. Among authors: ashcroft fm. Nature. 1997 May 8;387(6629):179-83. doi: 10.1038/387179a0. Nature. 1997. PMID: 9144288

8

Molecular determinants of KATP channel inhibition by ATP.

Tucker SJ, Gribble FM, Proks P, Trapp S, Ryder TJ, Haug T, Reimann F, Ashcroft FM. Tucker SJ, et al. Among authors: ashcroft fm. EMBO J. 1998 Jun 15;17(12):3290-6. doi: 10.1093/emboj/17.12.3290. EMBO J. 1998. PMID: 9628866 Free PMC article.

9

A touching case of channel regulation: the ATP-sensitive K+ channel.

Tucker SJ, Ashcroft FM. Tucker SJ, et al. Among authors: ashcroft fm. Curr Opin Neurobiol. 1998 Jun;8(3):316-20. doi: 10.1016/s0959-4388(98)80055-x. Curr Opin Neurobiol. 1998. PMID: 9687347 Review.

10

Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP.

Trapp S, Proks P, Tucker SJ, Ashcroft FM. Trapp S, et al. Among authors: ashcroft fm. J Gen Physiol. 1998 Sep;112(3):333-49. doi: 10.1085/jgp.112.3.333. J Gen Physiol. 1998. PMID: 9725893 Free PMC article.

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