Ganapathy-Kanniappan S - Search Results

1

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pyruvylated during 3-bromopyruvate mediated cancer cell death.

Ganapathy-Kanniappan S, Geschwind JF, Kunjithapatham R, Buijs M, Vossen JA, Tchernyshyov I, Cole RN, Syed LH, Rao PP, Ota S, Vali M. Ganapathy-Kanniappan S, et al. Anticancer Res. 2009 Dec;29(12):4909-18. Anticancer Res. 2009. PMID: 20044597 Free PMC article.

2

The pyruvic acid analog 3-bromopyruvate interferes with the tetrazolium reagent MTS in the evaluation of cytotoxicity.

Ganapathy-Kanniappan S, Geschwind JF, Kunjithapatham R, Buijs M, Syed LH, Rao PP, Ota S, Vali M. Ganapathy-Kanniappan S, et al. Assay Drug Dev Technol. 2010 Apr;8(2):258-62. doi: 10.1089/adt.2009.0226. Assay Drug Dev Technol. 2010. PMID: 20085459

3

3-Bromopyruvate induces endoplasmic reticulum stress, overcomes autophagy and causes apoptosis in human HCC cell lines.

Ganapathy-Kanniappan S, Geschwind JF, Kunjithapatham R, Buijs M, Syed LH, Rao PP, Ota S, Kwak BK, Loffroy R, Vali M. Ganapathy-Kanniappan S, et al. Anticancer Res. 2010 Mar;30(3):923-35. Anticancer Res. 2010. PMID: 20393016

4

Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists.

Ganapathy-Kanniappan S, Kunjithapatham R, Torbenson MS, Rao PP, Carson KA, Buijs M, Vali M, Geschwind JF. Ganapathy-Kanniappan S, et al. Radiology. 2012 Mar;262(3):834-45. doi: 10.1148/radiol.11111569. Radiology. 2012. PMID: 22357885 Free PMC article.

5

Glyceraldehyde-3-phosphate dehydrogenase: a promising target for molecular therapy in hepatocellular carcinoma.

Ganapathy-Kanniappan S, Kunjithapatham R, Geschwind JF. Ganapathy-Kanniappan S, et al. Oncotarget. 2012 Sep;3(9):940-53. doi: 10.18632/oncotarget.623. Oncotarget. 2012. PMID: 22964488 Free PMC article. Review.

6

Anticancer efficacy of the metabolic blocker 3-bromopyruvate: specific molecular targeting.

Ganapathy-Kanniappan S, Kunjithapatham R, Geschwind JF. Ganapathy-Kanniappan S, et al. Anticancer Res. 2013 Jan;33(1):13-20. Anticancer Res. 2013. PMID: 23267123 Review.

7

Occurrence of a multimeric high-molecular-weight glyceraldehyde-3-phosphate dehydrogenase in human serum.

Kunjithapatham R, Geschwind JF, Devine L, Boronina TN, O'Meally RN, Cole RN, Torbenson MS, Ganapathy-Kanniappan S. Kunjithapatham R, et al. J Proteome Res. 2015 Apr 3;14(4):1645-56. doi: 10.1021/acs.jproteome.5b00089. Epub 2015 Mar 18. J Proteome Res. 2015. PMID: 25734908 Free PMC article.

8

GAPDH with NAD⁺-binding site mutation competitively inhibits the wild-type and affects glucose metabolism in cancer.

Kunjithapatham R, Ganapathy-Kanniappan S. Kunjithapatham R, et al. Among authors: ganapathy kanniappan s. Biochim Biophys Acta Gen Subj. 2018 Dec;1862(12):2555-2563. doi: 10.1016/j.bbagen.2018.08.001. Epub 2018 Aug 3. Biochim Biophys Acta Gen Subj. 2018. PMID: 30077773

9

Targeting of VX2 rabbit liver tumor by selective delivery of 3-bromopyruvate: a biodistribution and survival study.

Vali M, Vossen JA, Buijs M, Engles JM, Liapi E, Ventura VP, Khwaja A, Acha-Ngwodo O, Ganapathy-Kanniappan S, Syed L, Wahl RL, Geschwind JF. Vali M, et al. J Pharmacol Exp Ther. 2008 Oct;327(1):32-7. doi: 10.1124/jpet.108.141093. Epub 2008 Jun 30. J Pharmacol Exp Ther. 2008. PMID: 18591216 Free PMC article.

10

Spontaneous tumor regression in a syngeneic rat model of liver cancer: implications for survival studies.

Buijs M, Geschwind JF, Syed LH, Ganapathy-Kanniappan S, Kunjithapatham R, Wijlemans JW, Kook Kwak B, Ota S, Vali M. Buijs M, et al. J Vasc Interv Radiol. 2012 Dec;23(12):1685-91. doi: 10.1016/j.jvir.2012.08.025. J Vasc Interv Radiol. 2012. PMID: 23177115 Free PMC article.

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