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The successful application of simulation-based training in thoracic surgery residency.
Burkhart HM, Riley JB, Hendrickson SE, Glenn GF, Lynch JJ, Arnold JJ, Dearani JA, Schaff HV, Sundt TM 3rd. Burkhart HM, et al. Among authors: arnold jj. J Thorac Cardiovasc Surg. 2010 Mar;139(3):707-12. doi: 10.1016/j.jtcvs.2009.10.029. Epub 2009 Dec 28. J Thorac Cardiovasc Surg. 2010. PMID: 20038482 Free article.
A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent.
Klein M, Das A, Bera SC, Anderson TK, Kocincova D, Lee HW, Wang B, Papini FS, Marecki JC, Arnold JJ, Cameron CE, Raney KD, Artsimovitch I, Götte M, Kirchdoerfer RN, Depken M, Dulin D. Klein M, et al. Among authors: arnold jj. bioRxiv [Preprint]. 2025 Jan 10:2025.01.10.632299. doi: 10.1101/2025.01.10.632299. bioRxiv. 2025. PMID: 39829827 Free PMC article. Preprint.
Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
Merten EM, Sears JD, Leisner TM, Hardy PB, Ghoshal A, Hossain MA, Asressu KH, Brown PJ, Tse EG, Stashko MA, Li K, Norris-Drouin JL, Herring LE, Mordant AL, Webb TS, Mills CA, Barker NK, Streblow ZJ, Perveen S, Arrowsmith CH, Couñago RM, Arnold JJ, Cameron CE, Streblow DN, Moorman NJ, Heise MT, Willson TM, Popov KI, Pearce KH. Merten EM, et al. Among authors: arnold jj. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2409166121. doi: 10.1073/pnas.2409166121. Epub 2024 Oct 10. Proc Natl Acad Sci U S A. 2024. PMID: 39388272
Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
Merten EM, Sears JD, Leisner TM, Hardy PB, Ghoshal A, Hossain MA, Asressu KH, Brown PJ, Stashko MA, Herring L, Mordant AL, Webb TS, Mills CA, Barker NK, Streblow ZJ, Perveen S, Arrowsmith C, Arnold JJ, Cameron CE, Streblow DN, Moorman NJ, Heise M, Willson TM, Popov K, Pearce KH. Merten EM, et al. Among authors: arnold jj. bioRxiv [Preprint]. 2024 May 23:2024.03.22.586341. doi: 10.1101/2024.03.22.586341. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2409166121. doi: 10.1073/pnas.2409166121 PMID: 38562906 Free PMC article. Updated. Preprint.
Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials.
Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Monés J, Singh RP, Ribeiro R, Wykoff CC; OAKS and DERBY study investigators. Heier JS, et al. Lancet. 2023 Oct 21;402(10411):1434-1448. doi: 10.1016/S0140-6736(23)01520-9. Lancet. 2023. PMID: 37865470 Clinical Trial.
Maintenance of a host-specific minority mutation in the West Nile virus NS3.
Caldwell HS, Kuo L, Pata JD, Dupuis AP 2nd, Arnold JJ, Yeager C, Stout J, Koetzner CA, Payne AF, Bialosuknia SM, Banker EM, Nolen TA, Cameron CE, Ciota AT. Caldwell HS, et al. Among authors: arnold jj. iScience. 2023 Jul 26;26(8):107468. doi: 10.1016/j.isci.2023.107468. eCollection 2023 Aug 18. iScience. 2023. PMID: 37593454 Free PMC article.
210 results