Beeler AB - Search Results

1

A time-resolved fluorescence-resonance energy transfer assay for identifying inhibitors of hepatitis C virus core dimerization.

Kota S, Scampavia L, Spicer T, Beeler AB, Takahashi V, Snyder JK, Porco JA, Hodder P, Strosberg AD. Kota S, et al. Among authors: beeler ab. Assay Drug Dev Technol. 2010 Feb;8(1):96-105. doi: 10.1089/adt.2009.0217. Assay Drug Dev Technol. 2010. PMID: 20035614 Free PMC article.

2

Stereochemical diversity through cyclodimerization: synthesis of polyketide-like macrodiolides.

Su Q, Beeler AB, Lobkovsky E, Porco JA Jr, Panek JS. Su Q, et al. Among authors: beeler ab. Org Lett. 2003 Jun 12;5(12):2149-52. doi: 10.1021/ol034608z. Org Lett. 2003. PMID: 12790551

3

Chemical library synthesis using convergent approaches.

Beeler AB, Schaus SE, Porco JA Jr. Beeler AB, et al. Curr Opin Chem Biol. 2005 Jun;9(3):277-84. doi: 10.1016/j.cbpa.2005.04.005. Curr Opin Chem Biol. 2005. PMID: 15939329 Review.

4

Convergent synthesis of a complex oxime library using chemical domain shuffling.

Su S, Acquilano DE, Arumugasamy J, Beeler AB, Eastwood EL, Giguere JR, Lan P, Lei X, Min GK, Yeager AR, Zhou Y, Panek JS, Snyder JK, Schaus SE, Porco JA Jr. Su S, et al. Among authors: beeler ab. Org Lett. 2005 Jun 23;7(13):2751-4. doi: 10.1021/ol051023r. Org Lett. 2005. PMID: 15957938

5

Synthesis of a library of complex macrodiolides employing cyclodimerization of hydroxy esters.

Beeler AB, Acquilano DE, Su Q, Yan F, Roth BL, Panek JS, Porco JA Jr. Beeler AB, et al. J Comb Chem. 2005 Sep-Oct;7(5):673-81. doi: 10.1021/cc050064b. J Comb Chem. 2005. PMID: 16153061

6

Convergent synthesis of complex diketopiperazines derived from pipecolic acid scaffolds and parallel screening against GPCR targets.

Dandapani S, Lan P, Beeler AB, Beischel S, Abbas A, Roth BL, Porco JA Jr, Panek JS. Dandapani S, et al. Among authors: beeler ab. J Org Chem. 2006 Nov 10;71(23):8934-45. doi: 10.1021/jo061758p. J Org Chem. 2006. PMID: 17081025

7

Discovery of chemical reactions through multidimensional screening.

Beeler AB, Su S, Singleton CA, Porco JA Jr. Beeler AB, et al. J Am Chem Soc. 2007 Feb 7;129(5):1413-9. doi: 10.1021/ja0674744. J Am Chem Soc. 2007. PMID: 17263426

8

Identification of novel epoxide inhibitors of hepatitis C virus replication using a high-throughput screen.

Peng LF, Kim SS, Matchacheep S, Lei X, Su S, Lin W, Runguphan W, Choe WH, Sakamoto N, Ikeda M, Kato N, Beeler AB, Porco JA Jr, Schreiber SL, Chung RT. Peng LF, et al. Among authors: beeler ab. Antimicrob Agents Chemother. 2007 Oct;51(10):3756-9. doi: 10.1128/AAC.00233-07. Epub 2007 Aug 6. Antimicrob Agents Chemother. 2007. PMID: 17682098 Free PMC article.

9

Nucleophilic addition to N-phosphinylimines by rare-earth-metal triflate/trifluoroacetic anhydride activation.

Ong WW, Beeler AB, Kesavan S, Panek JS, Porco JA Jr. Ong WW, et al. Among authors: beeler ab. Angew Chem Int Ed Engl. 2007;46(39):7470-2. doi: 10.1002/anie.200700694. Angew Chem Int Ed Engl. 2007. PMID: 17722135 No abstract available.

10

Library synthesis using 5,6,7,8-tetrahydro-1,6-naphthyridines as scaffolds.

Zhou Y, Beeler AB, Cho S, Wang Y, Franzblau SG, Snyder JK. Zhou Y, et al. Among authors: beeler ab. J Comb Chem. 2008 Jul-Aug;10(4):534-40. doi: 10.1021/cc800038r. Epub 2008 Jun 3. J Comb Chem. 2008. PMID: 18517255

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