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Prenatal exposure to apoE deficiency and postnatal hypercholesterolemia are associated with altered cell-specific lysine methyltransferase and histone methylation patterns in the vasculature.
Alkemade FE, van Vliet P, Henneman P, van Dijk KW, Hierck BP, van Munsteren JC, Scheerman JA, Goeman JJ, Havekes LM, Gittenberger-de Groot AC, van den Elsen PJ, DeRuiter MC. Alkemade FE, et al. Among authors: van munsteren jc, van dijk kw, van vliet p, van den elsen pj. Am J Pathol. 2010 Feb;176(2):542-8. doi: 10.2353/ajpath.2010.090031. Epub 2009 Dec 24. Am J Pathol. 2010. PMID: 20035052 Free PMC article.
In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 --> Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice.
van Vlijmen BJ, van Dijk KW, van't Hof HB, van Gorp PJ, van der Zee A, van der Boom H, Breuer ML, Hofker MH, Havekes LM. van Vlijmen BJ, et al. Among authors: van gorp pj, van dijk kw, van der boom h, van t hof hb, van der zee a. J Biol Chem. 1996 Nov 29;271(48):30595-602. doi: 10.1074/jbc.271.48.30595. J Biol Chem. 1996. PMID: 8940032 Free article.
In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.
Jong MC, Dahlmans VE, van Gorp PJ, van Dijk KW, Breuer ML, Hofker MH, Havekes LM. Jong MC, et al. Among authors: van gorp pj, van dijk kw. J Clin Invest. 1996 Nov 15;98(10):2259-67. doi: 10.1172/JCI119036. J Clin Invest. 1996. PMID: 8941642 Free PMC article.
Use of transgenic mice in lipoprotein metabolism and atherosclerosis research.
Havekes LM, van Vlijmen BJ, Jong MC, van Dijk KW, Hofker MH. Havekes LM, et al. Among authors: van vlijmen bj, van dijk kw. Prostaglandins Leukot Essent Fatty Acids. 1997 Oct;57(4-5):463-6. doi: 10.1016/s0952-3278(97)90429-4. Prostaglandins Leukot Essent Fatty Acids. 1997. PMID: 9430397
Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor.
van Dijk KW, van Vlijmen BJ, van der Zee A, van't Hof B, van der Boom H, Kobayashi K, Chan L, Havekes LM, Hofker MH. van Dijk KW, et al. Among authors: van vlijmen bj, van der boom h, van der zee a, van t hof b. Arterioscler Thromb Vasc Biol. 1998 Jan;18(1):7-12. doi: 10.1161/01.atv.18.1.7. Arterioscler Thromb Vasc Biol. 1998. PMID: 9445249
Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.
Jong MC, van Dijk KW, Dahlmans VE, Van der Boom H, Kobayashi K, Oka K, Siest G, Chan L, Hofker MH, Havekes LM. Jong MC, et al. Among authors: van dijk kw, van der boom h. Biochem J. 1999 Mar 1;338 ( Pt 2)(Pt 2):281-7. Biochem J. 1999. PMID: 10024503 Free PMC article.
203 results