Harrington LA - Search Results

1

The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization.

Sealey DC, Zheng L, Taboski MA, Cruickshank J, Ikura M, Harrington LA. Sealey DC, et al. Among authors: harrington la. Nucleic Acids Res. 2010 Apr;38(6):2019-35. doi: 10.1093/nar/gkp1160. Epub 2009 Dec 23. Nucleic Acids Res. 2010. PMID: 20034955 Free PMC article.

2

A mammalian telomerase-associated protein.

Harrington L, McPhail T, Mar V, Zhou W, Oulton R, Bass MB, Arruda I, Robinson MO. Harrington L, et al. Science. 1997 Feb 14;275(5302):973-7. doi: 10.1126/science.275.5302.973. Science. 1997. PMID: 9020079

3

Human telomerase contains evolutionarily conserved catalytic and structural subunits.

Harrington L, Zhou W, McPhail T, Oulton R, Yeung DS, Mar V, Bass MB, Robinson MO. Harrington L, et al. Genes Dev. 1997 Dec 1;11(23):3109-15. doi: 10.1101/gad.11.23.3109. Genes Dev. 1997. PMID: 9389643 Free PMC article.

4

Reconstitution of human telomerase activity in vitro.

Beattie TL, Zhou W, Robinson MO, Harrington L. Beattie TL, et al. Curr Biol. 1998 Jan 29;8(3):177-80. doi: 10.1016/s0960-9822(98)70067-3. Curr Biol. 1998. PMID: 9443919 Free article.

5

Telomeres, telomerase, and cancer: life on the edge of genomic stability.

Oulton R, Harrington L. Oulton R, et al. Curr Opin Oncol. 2000 Jan;12(1):74-81. doi: 10.1097/00001622-200001000-00013. Curr Opin Oncol. 2000. PMID: 10687733 Review.

6

Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo.

Liu Y, Snow BE, Hande MP, Baerlocher G, Kickhoefer VA, Yeung D, Wakeham A, Itie A, Siderovski DP, Lansdorp PM, Robinson MO, Harrington L. Liu Y, et al. Mol Cell Biol. 2000 Nov;20(21):8178-84. doi: 10.1128/MCB.20.21.8178-8184.2000. Mol Cell Biol. 2000. PMID: 11027287 Free PMC article.

7

Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding.

Beattie TL, Zhou W, Robinson MO, Harrington L. Beattie TL, et al. Mol Biol Cell. 2000 Oct;11(10):3329-40. doi: 10.1091/mbc.11.10.3329. Mol Biol Cell. 2000. PMID: 11029039 Free PMC article.

8

The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo.

Liu Y, Snow BE, Hande MP, Yeung D, Erdmann NJ, Wakeham A, Itie A, Siderovski DP, Lansdorp PM, Robinson MO, Harrington L. Liu Y, et al. Curr Biol. 2000 Nov 16;10(22):1459-62. doi: 10.1016/s0960-9822(00)00805-8. Curr Biol. 2000. PMID: 11102810 Free article.

9

Functional multimerization of the human telomerase reverse transcriptase.

Beattie TL, Zhou W, Robinson MO, Harrington L. Beattie TL, et al. Mol Cell Biol. 2001 Sep;21(18):6151-60. doi: 10.1128/MCB.21.18.6151-6160.2001. Mol Cell Biol. 2001. PMID: 11509658 Free PMC article.

10

Functional conservation of the telomerase protein Est1p in humans.

Snow BE, Erdmann N, Cruickshank J, Goldman H, Gill RM, Robinson MO, Harrington L. Snow BE, et al. Curr Biol. 2003 Apr 15;13(8):698-704. doi: 10.1016/s0960-9822(03)00210-0. Curr Biol. 2003. PMID: 12699629 Free article.

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