Rusinko A - Search Results

1

2,3-Diaminopyrazines as Rho kinase inhibitors.

Henderson AJ, Hadden M, Guo C, Douglas N, Decornez H, Hellberg MR, Rusinko A, McLaughlin M, Sharif N, Drace C, Patil R. Henderson AJ, et al. Among authors: rusinko a. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1137-40. doi: 10.1016/j.bmcl.2009.12.012. Epub 2009 Dec 5. Bioorg Med Chem Lett. 2010. PMID: 20022494

2

In vivo optimization of 2,3-diaminopyrazine Rho Kinase inhibitors for the treatment of glaucoma.

Chen HH, Namil A, Severns B, Ward J, Kelly C, Drace C, McLaughlin MA, Yacoub S, Li B, Patil R, Sharif N, Hellberg MR, Rusinko A, Pang IH, Combrink KD. Chen HH, et al. Among authors: rusinko a. Bioorg Med Chem Lett. 2014 Apr 15;24(8):1875-9. doi: 10.1016/j.bmcl.2014.03.017. Epub 2014 Mar 19. Bioorg Med Chem Lett. 2014. PMID: 24684843

3

A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole.

May JA, Chen HH, Rusinko A, Lynch VM, Sharif NA, McLaughlin MA. May JA, et al. Among authors: rusinko a. J Med Chem. 2003 Sep 11;46(19):4188-95. doi: 10.1021/jm030205t. J Med Chem. 2003. PMID: 12954071

4

Rapid Identification of Novel Inhibitors of the Human Aquaporin-1 Water Channel.

Patil RV, Xu S, van Hoek AN, Rusinko A, Feng Z, May J, Hellberg M, Sharif NA, Wax MB, Irigoyen M, Carr G, Brittain T, Brown P, Colbert D, Kumari S, Varadaraj K, Mitra AK. Patil RV, et al. Among authors: rusinko a. Chem Biol Drug Des. 2016 May;87(5):794-805. doi: 10.1111/cbdd.12713. Epub 2016 Jan 17. Chem Biol Drug Des. 2016. PMID: 26685080 Free PMC article.

5

Chemical and biochemical studies of 2-propynylpyrrolidine derivatives. Restricted-rotation analogues of N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide (BM-5).

Trybulski EJ, Kramss RH, Mangano RM, Rusinko A 3rd. Trybulski EJ, et al. Among authors: rusinko a 3rd. J Med Chem. 1990 Dec;33(12):3190-8. doi: 10.1021/jm00174a015. J Med Chem. 1990. PMID: 2258905

6

Analysis of a large structure/biological activity data set using recursive partitioning.

Rusinko A 3rd, Farmen MW, Lambert CG, Brown PL, Young SS. Rusinko A 3rd, et al. J Chem Inf Comput Sci. 1999 Nov-Dec;39(6):1017-26. doi: 10.1021/ci9903049. J Chem Inf Comput Sci. 1999. PMID: 10614024

7

Ocular pharmacokinetics of moxifloxacin after topical treatment of animals and humans.

Robertson SM, Curtis MA, Schlech BA, Rusinko A, Owen GR, Dembinska O, Liao J, Dahlin DC. Robertson SM, et al. Among authors: rusinko a. Surv Ophthalmol. 2005 Nov;50 Suppl 1:S32-45. doi: 10.1016/j.survophthal.2005.07.001. Surv Ophthalmol. 2005. PMID: 16257309 Review.

8

Optimization of focused chemical libraries using recursive partitioning.

Rusinko A 3rd, Young SS, Drewry DH, Gerritz SW. Rusinko A 3rd, et al. Comb Chem High Throughput Screen. 2002 Mar;5(2):125-33. doi: 10.2174/1386207024607383. Comb Chem High Throughput Screen. 2002. PMID: 11966421

9

Automated pharmacophore identification for large chemical data sets.

Chen X, Rusinko A 3rd, Tropsha A, Young SS. Chen X, et al. Among authors: rusinko a 3rd. J Chem Inf Comput Sci. 1999 Sep-Oct;39(5):887-96. doi: 10.1021/ci990327n. J Chem Inf Comput Sci. 1999. PMID: 10529987

10

Searching for pharmacophores in large coordinate data bases and its use in drug design.

Sheridan RP, Rusinko A 3rd, Nilakantan R, Venkataraghavan R. Sheridan RP, et al. Among authors: rusinko a 3rd. Proc Natl Acad Sci U S A. 1989 Oct;86(20):8165-9. doi: 10.1073/pnas.86.20.8165. Proc Natl Acad Sci U S A. 1989. PMID: 2813386 Free PMC article.

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