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2,3-Diaminopyrazines as Rho kinase inhibitors.
Henderson AJ, Hadden M, Guo C, Douglas N, Decornez H, Hellberg MR, Rusinko A, McLaughlin M, Sharif N, Drace C, Patil R. Henderson AJ, et al. Among authors: hellberg mr. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1137-40. doi: 10.1016/j.bmcl.2009.12.012. Epub 2009 Dec 5. Bioorg Med Chem Lett. 2010. PMID: 20022494
Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma.
Davis RL, Kahraman M, Prins TJ, Beaver Y, Cook TG, Cramp J, Cayanan CS, Gardiner EM, McLaughlin MA, Clark AF, Hellberg MR, Shiau AK, Noble SA, Borchardt AJ. Davis RL, et al. Among authors: hellberg mr. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3361-6. doi: 10.1016/j.bmcl.2010.04.020. Epub 2010 Apr 11. Bioorg Med Chem Lett. 2010. PMID: 20434334
3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents.
Hellberg MR, Conrow RE, Sharif NA, McLaughlin MA, Bishop JE, Crider JY, Dean WD, DeWolf KA, Pierce DR, Sallee VL, Selliah RD, Severns BS, Sproull SJ, Williams GW, Zinke PW, Klimko PG. Hellberg MR, et al. Bioorg Med Chem. 2002 Jun;10(6):2031-49. doi: 10.1016/s0968-0896(02)00016-0. Bioorg Med Chem. 2002. PMID: 11937363
Rapid Identification of Novel Inhibitors of the Human Aquaporin-1 Water Channel.
Patil RV, Xu S, van Hoek AN, Rusinko A, Feng Z, May J, Hellberg M, Sharif NA, Wax MB, Irigoyen M, Carr G, Brittain T, Brown P, Colbert D, Kumari S, Varadaraj K, Mitra AK. Patil RV, et al. Chem Biol Drug Des. 2016 May;87(5):794-805. doi: 10.1111/cbdd.12713. Epub 2016 Jan 17. Chem Biol Drug Des. 2016. PMID: 26685080 Free PMC article.
22 results