Grady WM - Search Results

1

TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer.

Baek JY, Morris SM, Campbell J, Fausto N, Yeh MM, Grady WM. Baek JY, et al. Among authors: grady wm. Int J Cancer. 2010 Sep 1;127(5):1060-71. doi: 10.1002/ijc.25127. Int J Cancer. 2010. PMID: 20020490 Free PMC article.

2

Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas.

Grady WM, Rajput A, Myeroff L, Liu DF, Kwon K, Willis J, Markowitz S. Grady WM, et al. Cancer Res. 1998 Jul 15;58(14):3101-4. Cancer Res. 1998. PMID: 9679977

3

Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers.

Grady WM, Myeroff LL, Swinler SE, Rajput A, Thiagalingam S, Lutterbaugh JD, Neumann A, Brattain MG, Chang J, Kim SJ, Kinzler KW, Vogelstein B, Willson JK, Markowitz S. Grady WM, et al. Cancer Res. 1999 Jan 15;59(2):320-4. Cancer Res. 1999. PMID: 9927040

4

Proliferation and Cdk4 expression in microsatellite unstable colon cancers with TGFBR2 mutations.

Grady WM, Willis JE, Trobridge P, Romero-Gallo J, Munoz N, Olechnowicz J, Ferguson K, Gautam S, Markowitz SD. Grady WM, et al. Int J Cancer. 2006 Feb 1;118(3):600-8. doi: 10.1002/ijc.21399. Int J Cancer. 2006. PMID: 16108056

5

Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.

Muñoz NM, Upton M, Rojas A, Washington MK, Lin L, Chytil A, Sozmen EG, Madison BB, Pozzi A, Moon RT, Moses HL, Grady WM. Muñoz NM, et al. Among authors: grady wm. Cancer Res. 2006 Oct 15;66(20):9837-44. doi: 10.1158/0008-5472.CAN-06-0890. Cancer Res. 2006. PMID: 17047044

6

The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer.

Rojas A, Meherem S, Kim YH, Washington MK, Willis JE, Markowitz SD, Grady WM. Rojas A, et al. Among authors: grady wm. Int J Cancer. 2008 Jul 1;123(1):14-21. doi: 10.1002/ijc.23608. Int J Cancer. 2008. PMID: 18425817 Free PMC article.

7

TGF-beta has paradoxical and context dependent effects on proliferation and anoikis in human colorectal cancer cell lines.

Muñoz NM, Baek JY, Grady WM. Muñoz NM, et al. Among authors: grady wm. Growth Factors. 2008 Oct;26(5):254-62. doi: 10.1080/08977190802291667. Growth Factors. 2008. PMID: 18651288 Free PMC article.

8

TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway.

Trobridge P, Knoblaugh S, Washington MK, Munoz NM, Tsuchiya KD, Rojas A, Song X, Ulrich CM, Sasazuki T, Shirasawa S, Grady WM. Trobridge P, et al. Among authors: grady wm. Gastroenterology. 2009 May;136(5):1680-8.e7. doi: 10.1053/j.gastro.2009.01.066. Epub 2009 Feb 4. Gastroenterology. 2009. PMID: 19208363 Free PMC article.

9

Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss.

Morris SM, Baek JY, Koszarek A, Kanngurn S, Knoblaugh SE, Grady WM. Morris SM, et al. Among authors: grady wm. Hepatology. 2012 Jan;55(1):121-31. doi: 10.1002/hep.24653. Epub 2011 Dec 6. Hepatology. 2012. PMID: 21898503 Free PMC article.

10

Inactivation of TGF-β signaling and loss of PTEN cooperate to induce colon cancer in vivo.

Yu M, Trobridge P, Wang Y, Kanngurn S, Morris SM, Knoblaugh S, Grady WM. Yu M, et al. Among authors: grady wm. Oncogene. 2014 Mar 20;33(12):1538-47. doi: 10.1038/onc.2013.102. Epub 2013 Apr 22. Oncogene. 2014. PMID: 23604118 Free PMC article.

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