Franklin CC - Search Results

1

Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis.

Thompson JA, Franklin CC. Thompson JA, et al. Among authors: franklin cc. Toxicol Lett. 2010 Mar 1;193(1):33-40. doi: 10.1016/j.toxlet.2009.12.004. Epub 2009 Dec 16. Toxicol Lett. 2010. PMID: 20006689 Free PMC article.

2

Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes.

Thompson JA, White CC, Cox DP, Chan JY, Kavanagh TJ, Fausto N, Franklin CC. Thompson JA, et al. Among authors: franklin cc. Free Radic Biol Med. 2009 Jun 15;46(12):1614-25. doi: 10.1016/j.freeradbiomed.2009.03.016. Epub 2009 Mar 26. Free Radic Biol Med. 2009. PMID: 19328227 Free PMC article.

3

Manipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicity.

Backos DS, Brocker CN, Franklin CC. Backos DS, et al. Among authors: franklin cc. Toxicol Appl Pharmacol. 2010 Feb 15;243(1):35-45. doi: 10.1016/j.taap.2009.11.010. Epub 2009 Nov 13. Toxicol Appl Pharmacol. 2010. PMID: 19914271 Free PMC article.

4

The role of glutathione in brain tumor drug resistance.

Backos DS, Franklin CC, Reigan P. Backos DS, et al. Among authors: franklin cc. Biochem Pharmacol. 2012 Apr 15;83(8):1005-12. doi: 10.1016/j.bcp.2011.11.016. Epub 2011 Nov 28. Biochem Pharmacol. 2012. PMID: 22138445 Review.

5

Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase.

Franklin CC, Backos DS, Mohar I, White CC, Forman HJ, Kavanagh TJ. Franklin CC, et al. Mol Aspects Med. 2009 Feb-Apr;30(1-2):86-98. doi: 10.1016/j.mam.2008.08.009. Epub 2008 Sep 6. Mol Aspects Med. 2009. PMID: 18812186 Free PMC article. Review.

6

Posttranslational modification and regulation of glutamate-cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenal.

Backos DS, Fritz KS, Roede JR, Petersen DR, Franklin CC. Backos DS, et al. Among authors: franklin cc. Free Radic Biol Med. 2011 Jan 1;50(1):14-26. doi: 10.1016/j.freeradbiomed.2010.10.694. Epub 2010 Oct 21. Free Radic Biol Med. 2011. PMID: 20970495 Free PMC article.

7

Oxidative Stress and the ER Stress Response in a Murine Model for Early-Stage Alcoholic Liver Disease.

Galligan JJ, Smathers RL, Shearn CT, Fritz KS, Backos DS, Jiang H, Franklin CC, Orlicky DJ, Maclean KN, Petersen DR. Galligan JJ, et al. Among authors: franklin cc. J Toxicol. 2012;2012:207594. doi: 10.1155/2012/207594. Epub 2012 Jul 5. J Toxicol. 2012. PMID: 22829816 Free PMC article.

8

A synthetic chalcone as a potent inducer of glutathione biosynthesis.

Kachadourian R, Day BJ, Pugazhenti S, Franklin CC, Genoux-Bastide E, Mahaffey G, Gauthier C, Di Pietro A, Boumendjel A. Kachadourian R, et al. Among authors: franklin cc. J Med Chem. 2012 Feb 9;55(3):1382-8. doi: 10.1021/jm2016073. Epub 2012 Jan 30. J Med Chem. 2012. PMID: 22239485 Free PMC article.

9

Glycation of glutamate cysteine ligase by 2-deoxy-d-ribose and its potential impact on chemoresistance in glioblastoma.

Backos DS, Fritz KS, McArthur DG, Kepa JK, Donson AM, Petersen DR, Foreman NK, Franklin CC, Reigan P. Backos DS, et al. Among authors: franklin cc. Neurochem Res. 2013 Sep;38(9):1838-49. doi: 10.1007/s11064-013-1090-4. Epub 2013 Jun 7. Neurochem Res. 2013. PMID: 23743623

10

Methods to detect protein glutathionylation.

Poerschke RL, Fritz KS, Franklin CC. Poerschke RL, et al. Among authors: franklin cc. Curr Protoc Toxicol. 2013 Sep 23;57:6.17.1-6.17.18. doi: 10.1002/0471140856.tx0617s57. Curr Protoc Toxicol. 2013. PMID: 24510510

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