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Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2.
Hayden RE, Pratt G, Davies NJ, Khanim FL, Birtwistle J, Delgado J, Pearce C, Sant T, Drayson MT, Bunce CM. Hayden RE, et al. Among authors: birtwistle j. Leukemia. 2009 Feb;23(2):292-304. doi: 10.1038/leu.2008.283. Epub 2008 Oct 16. Leukemia. 2009. PMID: 18923439
Measurement of antibodies to pneumococcal, meningococcal and haemophilus polysaccharides, and tetanus and diphtheria toxoids using a 19-plexed assay.
Whitelegg AM, Birtwistle J, Richter A, Campbell JP, Turner JE, Ahmed TM, Giles LJ, Fellows M, Plant T, Ferraro AJ, Cobbold M, Drayson MT, MacLennan CA. Whitelegg AM, et al. Among authors: birtwistle j. J Immunol Methods. 2012 Mar 30;377(1-2):37-46. doi: 10.1016/j.jim.2012.01.007. Epub 2012 Jan 24. J Immunol Methods. 2012. PMID: 22293629 Free article.
Development of a highly-sensitive multi-plex assay using monoclonal antibodies for the simultaneous measurement of kappa and lambda immunoglobulin free light chains in serum and urine.
Campbell JP, Cobbold M, Wang Y, Goodall M, Bonney SL, Chamba A, Birtwistle J, Plant T, Afzal Z, Jefferis R, Drayson MT. Campbell JP, et al. Among authors: birtwistle j. J Immunol Methods. 2013 May 31;391(1-2):1-13. doi: 10.1016/j.jim.2013.01.014. Epub 2013 Feb 4. J Immunol Methods. 2013. PMID: 23388695 Free article.
Poor functional antibody responses are present in nearly all patients with chronic lymphocytic leukaemia, irrespective of total IgG concentration, and are associated with increased risk of infection.
Parry HM, Birtwistle J, Whitelegg A, Hudson C, McSkeane T, Hazlewood P, Mudongo N, Pratt G, Moss P, Drayson MT, Murray J, Richter AG. Parry HM, et al. Among authors: birtwistle j. Br J Haematol. 2015 Dec;171(5):887-90. doi: 10.1111/bjh.13455. Epub 2015 Apr 28. Br J Haematol. 2015. PMID: 25920967 Free article. No abstract available.
Brief Report: Immunization of HIV-Infected Adults in the UK With Haemophilus influenzae b/Meningococcal C Glycoconjugate and Pneumococcal Polysaccharide Vaccines.
MacLennan CA, Richter A, Hodson J, Faustini S, Birtwistle J, Whitelegg A, Chigiga J, Singo M, Walker-Haywood J, Mulugeta B, Masuka S, Mainey C, Plant T, Drayson MT, Manavi K. MacLennan CA, et al. Among authors: birtwistle j. J Acquir Immune Defic Syndr. 2016 Nov 1;73(3):287-293. doi: 10.1097/QAI.0000000000001054. J Acquir Immune Defic Syndr. 2016. PMID: 27163175
Comparison of short- and long-term humoral immune responses to pneumococcal polysaccharide and glycoconjugate vaccines in an HIV-infected population.
Faustini SE, Hodson J, Birtwistle J, Whitelegg A, Masuka S, Singo M, Chigiga J, Shields A, Plant T, Drayson MT, Manavi K, MacLennan CA, Richter AG. Faustini SE, et al. Among authors: birtwistle j. J Infect. 2024 Nov;89(5):106282. doi: 10.1016/j.jinf.2024.106282. Epub 2024 Sep 24. J Infect. 2024. PMID: 39326516 Free article.
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