Bixler GV - Search Results

1

A multistep validation process of biomarkers for preclinical drug development.

Freeman WM, Bixler GV, Brucklacher RM, Lin CM, Patel KM, VanGuilder HD, LaNoue KF, Kimball SR, Barber AJ, Antonetti DA, Gardner TW, Bronson SK. Freeman WM, et al. Among authors: bixler gv. Pharmacogenomics J. 2010 Oct;10(5):385-95. doi: 10.1038/tpj.2009.60. Epub 2009 Dec 8. Pharmacogenomics J. 2010. PMID: 19997081

2

Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response.

Brucklacher RM, Patel KM, VanGuilder HD, Bixler GV, Barber AJ, Antonetti DA, Lin CM, LaNoue KF, Gardner TW, Bronson SK, Freeman WM. Brucklacher RM, et al. Among authors: bixler gv. BMC Med Genomics. 2008 Jun 13;1:26. doi: 10.1186/1755-8794-1-26. BMC Med Genomics. 2008. PMID: 18554398 Free PMC article.

3

Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy.

VanGuilder HD, Bixler GV, Kutzler L, Brucklacher RM, Bronson SK, Kimball SR, Freeman WM. VanGuilder HD, et al. Among authors: bixler gv. PLoS One. 2011 Jan 13;6(1):e16271. doi: 10.1371/journal.pone.0016271. PLoS One. 2011. PMID: 21249158 Free PMC article.

4

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome.

Bixler GV, Vanguilder HD, Brucklacher RM, Kimball SR, Bronson SK, Freeman WM. Bixler GV, et al. BMC Med Genomics. 2011 May 15;4:40. doi: 10.1186/1755-8794-4-40. BMC Med Genomics. 2011. PMID: 21575160 Free PMC article.

5

Insulin treatment normalizes retinal neuroinflammation but not markers of synapse loss in diabetic rats.

Masser DR, VanGuilder Starkey HD, Bixler GV, Dunton W, Bronson SK, Freeman WM. Masser DR, et al. Among authors: bixler gv. Exp Eye Res. 2014 Aug;125:95-106. doi: 10.1016/j.exer.2014.06.005. Epub 2014 Jun 12. Exp Eye Res. 2014. PMID: 24931083 Free PMC article.

6

Hippocampal expression of myelin-associated inhibitors is induced with age-related cognitive decline and correlates with deficits of spatial learning and memory.

Vanguilder HD, Bixler GV, Sonntag WE, Freeman WM. Vanguilder HD, et al. Among authors: bixler gv. J Neurochem. 2012 Apr;121(1):77-98. doi: 10.1111/j.1471-4159.2012.07671.x. Epub 2012 Feb 10. J Neurochem. 2012. PMID: 22269040 Free PMC article.

7

Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment.

VanGuilder HD, Bixler GV, Brucklacher RM, Farley JA, Yan H, Warrington JP, Sonntag WE, Freeman WM. VanGuilder HD, et al. Among authors: bixler gv. J Neuroinflammation. 2011 Oct 11;8:138. doi: 10.1186/1742-2094-8-138. J Neuroinflammation. 2011. PMID: 21989322 Free PMC article.

8

Retinal gene expression responses to aging are sexually divergent.

Du M, Mangold CA, Bixler GV, Brucklacher RM, Masser DR, Stout MB, Elliott MH, Freeman WM. Du M, et al. Among authors: bixler gv. Mol Vis. 2017 Oct 10;23:707-717. eCollection 2017. Mol Vis. 2017. PMID: 29062222 Free PMC article.

9

Hippocampal subregions exhibit both distinct and shared transcriptomic responses to aging and nonneurodegenerative cognitive decline.

Masser DR, Bixler GV, Brucklacher RM, Yan H, Giles CB, Wren JD, Sonntag WE, Freeman WM. Masser DR, et al. Among authors: bixler gv. J Gerontol A Biol Sci Med Sci. 2014 Nov;69(11):1311-24. doi: 10.1093/gerona/glu091. Epub 2014 Jul 2. J Gerontol A Biol Sci Med Sci. 2014. PMID: 24994846 Free PMC article.

10

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging.

Mangold CA, Wronowski B, Du M, Masser DR, Hadad N, Bixler GV, Brucklacher RM, Ford MM, Sonntag WE, Freeman WM. Mangold CA, et al. Among authors: bixler gv. J Neuroinflammation. 2017 Jul 21;14(1):141. doi: 10.1186/s12974-017-0920-8. J Neuroinflammation. 2017. PMID: 28732515 Free PMC article.

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