Rubinsztein DC - Search Results

1

alpha Pix enhances mutant huntingtin aggregation.

Eriguchi M, Mizuta H, Luo S, Kuroda Y, Hara H, Rubinsztein DC. Eriguchi M, et al. Among authors: rubinsztein dc. J Neurol Sci. 2010 Mar 15;290(1-2):80-5. doi: 10.1016/j.jns.2009.11.003. Epub 2009 Dec 6. J Neurol Sci. 2010. PMID: 19969308

2

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

Ravikumar B, Vacher C, Berger Z, Davies JE, Luo S, Oroz LG, Scaravilli F, Easton DF, Duden R, O'Kane CJ, Rubinsztein DC. Ravikumar B, et al. Among authors: rubinsztein dc. Nat Genet. 2004 Jun;36(6):585-95. doi: 10.1038/ng1362. Epub 2004 May 16. Nat Genet. 2004. PMID: 15146184

3

Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity.

Luo S, Vacher C, Davies JE, Rubinsztein DC. Luo S, et al. Among authors: rubinsztein dc. J Cell Biol. 2005 May 23;169(4):647-56. doi: 10.1083/jcb.200412071. J Cell Biol. 2005. PMID: 15911879 Free PMC article.

4

Deleterious and protective properties of an aggregate-prone protein with a polyalanine expansion.

Berger Z, Davies JE, Luo S, Pasco MY, Majoul I, O'Kane CJ, Rubinsztein DC. Berger Z, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2006 Feb 1;15(3):453-65. doi: 10.1093/hmg/ddi460. Epub 2005 Dec 21. Hum Mol Genet. 2006. PMID: 16371423

5

Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin.

Yang H, Zhong X, Ballar P, Luo S, Shen Y, Rubinsztein DC, Monteiro MJ, Fang S. Yang H, et al. Among authors: rubinsztein dc. Exp Cell Res. 2007 Feb 1;313(3):538-50. doi: 10.1016/j.yexcr.2006.10.031. Epub 2006 Nov 3. Exp Cell Res. 2007. PMID: 17141218

6

Atg5 and Bcl-2 provide novel insights into the interplay between apoptosis and autophagy.

Luo S, Rubinsztein DC. Luo S, et al. Among authors: rubinsztein dc. Cell Death Differ. 2007 Jul;14(7):1247-50. doi: 10.1038/sj.cdd.4402149. Epub 2007 Apr 13. Cell Death Differ. 2007. PMID: 17431417 Review. No abstract available.

7

p21-activated kinase 1 promotes soluble mutant huntingtin self-interaction and enhances toxicity.

Luo S, Mizuta H, Rubinsztein DC. Luo S, et al. Among authors: rubinsztein dc. Hum Mol Genet. 2008 Mar 15;17(6):895-905. doi: 10.1093/hmg/ddm362. Epub 2007 Dec 7. Hum Mol Genet. 2008. PMID: 18065495

8

Huntingtin promotes cell survival by preventing Pak2 cleavage.

Luo S, Rubinsztein DC. Luo S, et al. Among authors: rubinsztein dc. J Cell Sci. 2009 Mar 15;122(Pt 6):875-85. doi: 10.1242/jcs.050013. Epub 2009 Feb 24. J Cell Sci. 2009. PMID: 19240112 Free PMC article.

9

Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL.

Luo S, Rubinsztein DC. Luo S, et al. Among authors: rubinsztein dc. Cell Death Differ. 2010 Feb;17(2):268-77. doi: 10.1038/cdd.2009.121. Epub 2009 Aug 28. Cell Death Differ. 2010. PMID: 19713971 Free PMC article.

10

Cytoprotective roles for autophagy.

Moreau K, Luo S, Rubinsztein DC. Moreau K, et al. Among authors: rubinsztein dc. Curr Opin Cell Biol. 2010 Apr;22(2):206-11. doi: 10.1016/j.ceb.2009.12.002. Epub 2010 Jan 4. Curr Opin Cell Biol. 2010. PMID: 20045304 Free PMC article. Review.

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