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Transfusion-dependency at presentation and its acquisition in the first year of diagnosis are both equally detrimental for survival in primary myelofibrosis--prognostic relevance is independent of IPSS or karyotype.
Tefferi A, Siragusa S, Hussein K, Schwager SM, Hanson CA, Pardanani A, Cervantes F, Passamonti F. Tefferi A, et al. Among authors: hussein k. Am J Hematol. 2010 Jan;85(1):14-7. doi: 10.1002/ajh.21574. Am J Hematol. 2010. PMID: 20029953 Free article.
Phase1/-2 study of Pomalidomide in myelofibrosis.
Mesa RA, Pardanani AD, Hussein K, Wu W, Schwager S, Litzow MR, Hogan WJ, Tefferi A. Mesa RA, et al. Among authors: hussein k. Am J Hematol. 2010 Feb;85(2):129-30. doi: 10.1002/ajh.21598. Am J Hematol. 2010. PMID: 20052748 Free article. Clinical Trial. No abstract available.
JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival.
Tefferi A, Lasho TL, Patnaik MM, Finke CM, Hussein K, Hogan WJ, Elliott MA, Litzow MR, Hanson CA, Pardanani A. Tefferi A, et al. Among authors: hussein k. Leukemia. 2010 Jan;24(1):105-9. doi: 10.1038/leu.2009.225. Epub 2009 Oct 22. Leukemia. 2010. PMID: 19847199
512 results