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Mechanisms of beta-cell death in type 2 diabetes.
Donath MY, Ehses JA, Maedler K, Schumann DM, Ellingsgaard H, Eppler E, Reinecke M. Donath MY, et al. Diabetes. 2005 Dec;54 Suppl 2:S108-13. doi: 10.2337/diabetes.54.suppl_2.s108. Diabetes. 2005. PMID: 16306327 Review.
Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1.
Maedler K, Schumann DM, Schulthess F, Oberholzer J, Bosco D, Berney T, Donath MY. Maedler K, et al. Among authors: donath my. Diabetes. 2006 Sep;55(9):2455-62. doi: 10.2337/db05-1586. Diabetes. 2006. Retraction in: Diabetes. 2020 Mar;69(3):494. doi: 10.2337/db20-rt03b PMID: 16936193 Retracted.
Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets.
Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, Iwakura Y, Oberholzer J, Wollheim CB, Gauthier BR, Donath MY. Maedler K, et al. Among authors: donath my. Diabetes. 2006 Oct;55(10):2713-22. doi: 10.2337/db05-1430. Diabetes. 2006. Retraction in: Diabetes. 2020 Mar;69(3):493. doi: 10.2337/db20-rt03a PMID: 17003335 Retracted.
The Fas pathway is involved in pancreatic beta cell secretory function.
Schumann DM, Maedler K, Franklin I, Konrad D, Størling J, Böni-Schnetzler M, Gjinovci A, Kurrer MO, Gauthier BR, Bosco D, Andres A, Berney T, Greter M, Becher B, Chervonsky AV, Halban PA, Mandrup-Poulsen T, Wollheim CB, Donath MY. Schumann DM, et al. Among authors: donath my. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2861-6. doi: 10.1073/pnas.0611487104. Epub 2007 Feb 13. Proc Natl Acad Sci U S A. 2007. PMID: 17299038 Free PMC article.
Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.
Ehses JA, Meier DT, Wueest S, Rytka J, Boller S, Wielinga PY, Schraenen A, Lemaire K, Debray S, Van Lommel L, Pospisilik JA, Tschopp O, Schultze SM, Malipiero U, Esterbauer H, Ellingsgaard H, Rütti S, Schuit FC, Lutz TA, Böni-Schnetzler M, Konrad D, Donath MY. Ehses JA, et al. Among authors: donath my. Diabetologia. 2010 Aug;53(8):1795-806. doi: 10.1007/s00125-010-1747-3. Epub 2010 Apr 21. Diabetologia. 2010. PMID: 20407745
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.
Ellingsgaard H, Hauselmann I, Schuler B, Habib AM, Baggio LL, Meier DT, Eppler E, Bouzakri K, Wueest S, Muller YD, Hansen AM, Reinecke M, Konrad D, Gassmann M, Reimann F, Halban PA, Gromada J, Drucker DJ, Gribble FM, Ehses JA, Donath MY. Ellingsgaard H, et al. Among authors: donath my. Nat Med. 2011 Oct 30;17(11):1481-9. doi: 10.1038/nm.2513. Nat Med. 2011. PMID: 22037645 Free PMC article.
186 results