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Identification of Highly Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomimetics with P2 Tetrahydrofuranylglycine.
Hidaka K, Kimura T, Sankaranarayanan R, Wang J, McDaniel KF, Kempf DJ, Kameoka M, Adachi M, Kuroki R, Nguyen JT, Hayashi Y, Kiso Y. Hidaka K, et al. Among authors: adachi m. J Med Chem. 2018 Jun 28;61(12):5138-5153. doi: 10.1021/acs.jmedchem.7b01709. Epub 2018 Jun 11. J Med Chem. 2018. PMID: 29852069
Crystallization and preliminary neutron diffraction studies of HIV-1 protease cocrystallized with inhibitor KNI-272.
Matsumura H, Adachi M, Sugiyama S, Okada S, Yamakami M, Tamada T, Hidaka K, Hayashi Y, Kimura T, Kiso Y, Kitatani T, Maki S, Yoshikawa HY, Adachi H, Takano K, Murakami S, Inoue T, Kuroki R, Mori Y. Matsumura H, et al. Among authors: adachi h, adachi m. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Nov 1;64(Pt 11):1003-6. doi: 10.1107/S1744309108029679. Epub 2008 Oct 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18997326 Free PMC article.
Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallography.
Adachi M, Ohhara T, Kurihara K, Tamada T, Honjo E, Okazaki N, Arai S, Shoyama Y, Kimura K, Matsumura H, Sugiyama S, Adachi H, Takano K, Mori Y, Hidaka K, Kimura T, Hayashi Y, Kiso Y, Kuroki R. Adachi M, et al. Among authors: adachi h. Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4641-6. doi: 10.1073/pnas.0809400106. Epub 2009 Mar 9. Proc Natl Acad Sci U S A. 2009. PMID: 19273847 Free PMC article.
Seven cysteine-deficient mutants depict the interplay between thermal and chemical stabilities of individual cysteine residues in mitogen-activated protein kinase c-Jun N-terminal kinase 1.
Nakaniwa T, Fukada H, Inoue T, Gouda M, Nakai R, Kirii Y, Adachi M, Tamada T, Segawa S, Kuroki R, Tada T, Kinoshita T. Nakaniwa T, et al. Among authors: adachi m. Biochemistry. 2012 Oct 23;51(42):8410-21. doi: 10.1021/bi300918w. Epub 2012 Oct 11. Biochemistry. 2012. PMID: 23020677
Mutagenesis of the crystal contact of acidic fibroblast growth factor.
Honjo E, Tamada T, Adachi M, Kuroki R, Meher A, Blaber M. Honjo E, et al. Among authors: adachi m. J Synchrotron Radiat. 2008 May;15(Pt 3):285-7. doi: 10.1107/S0909049508004470. Epub 2008 Apr 18. J Synchrotron Radiat. 2008. PMID: 18421160 Free PMC article.
2,204 results