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Scaffold hopping from pyridones to imidazo[1,2-a]pyridines. New positive allosteric modulators of metabotropic glutamate 2 receptor.
Tresadern G, Cid JM, Macdonald GJ, Vega JA, de Lucas AI, García A, Matesanz E, Linares ML, Oehlrich D, Lavreysen H, Biesmans I, Trabanco AA. Tresadern G, et al. Among authors: garcia a. Bioorg Med Chem Lett. 2010 Jan 1;20(1):175-9. doi: 10.1016/j.bmcl.2009.11.008. Epub 2009 Nov 10. Bioorg Med Chem Lett. 2010. PMID: 19932615
Imidazo[1,2-a]pyridines: orally active positive allosteric modulators of the metabotropic glutamate 2 receptor.
Trabanco AA, Tresadern G, Macdonald GJ, Vega JA, de Lucas AI, Matesanz E, García A, Linares ML, Alonso de Diego SA, Alonso JM, Oehlrich D, Ahnaou A, Drinkenburg W, Mackie C, Andrés JI, Lavreysen H, Cid JM. Trabanco AA, et al. Among authors: garcia a. J Med Chem. 2012 Mar 22;55(6):2688-701. doi: 10.1021/jm201561r. Epub 2012 Mar 1. J Med Chem. 2012. PMID: 22352782
Discovery of 3-cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-a]pyridine (JNJ-42153605): a positive allosteric modulator of the metabotropic glutamate 2 receptor.
Cid JM, Tresadern G, Vega JA, de Lucas AI, Matesanz E, Iturrino L, Linares ML, Garcia A, Andrés JI, Macdonald GJ, Oehlrich D, Lavreysen H, Megens A, Ahnaou A, Drinkenburg W, Mackie C, Pype S, Gallacher D, Trabanco AA. Cid JM, et al. Among authors: garcia a. J Med Chem. 2012 Oct 25;55(20):8770-89. doi: 10.1021/jm3010724. Epub 2012 Oct 16. J Med Chem. 2012. PMID: 23072213
Discovery of 8-Trifluoromethyl-3-cyclopropylmethyl-7-[(4-(2,4-difluorophenyl)-1-piperazinyl)methyl]-1,2,4-triazolo[4,3-a]pyridine (JNJ-46356479), a Selective and Orally Bioavailable mGlu2 Receptor Positive Allosteric Modulator (PAM).
Cid JM, Tresadern G, Vega JA, de Lucas AI, Del Cerro A, Matesanz E, Linares ML, García A, Iturrino L, Pérez-Benito L, Macdonald GJ, Oehlrich D, Lavreysen H, Peeters L, Ceusters M, Ahnaou A, Drinkenburg W, Mackie C, Somers M, Trabanco AA. Cid JM, et al. Among authors: garcia a. J Med Chem. 2016 Sep 22;59(18):8495-507. doi: 10.1021/acs.jmedchem.6b00913. Epub 2016 Sep 9. J Med Chem. 2016. PMID: 27579727
Blood immunophenotyping of multiple sclerosis patients at diagnosis identifies a classical monocyte subset associated to disease evolution.
Rodriguez S, Couloume L, Ferrant J, Vince N, Mandon M, Jean R, Monvoisin C, Leonard S, Le Gallou S, Silva NSB, Bourguiba-Hachemi S, Laplaud D, Garcia A, Casey R, Zephir H, Kerbrat A, Edan G, Lepage E, Thouvenot E, Ruet A, Mathey G, Gourraud PA, Tarte K, Delaloy C, Amé P, Roussel M, Michel L. Rodriguez S, et al. Among authors: garcia a. Front Immunol. 2025 Jan 8;15:1494842. doi: 10.3389/fimmu.2024.1494842. eCollection 2024. Front Immunol. 2025. PMID: 39845960 Free PMC article.
Platinum hydride formation during cathodic corrosion in aqueous solutions.
Hersbach TJP, Garcia-Esparza AT, Hanselman S, Paredes Mellone OA, Hoogenboom T, McCrum IT, Anastasiadou D, Feaster JT, Jaramillo TF, Vinson J, Kroll T, Garcia AC, Krtil P, Sokaras D, Koper MTM. Hersbach TJP, et al. Among authors: garcia ac. Nat Mater. 2025 Jan 22. doi: 10.1038/s41563-024-02080-y. Online ahead of print. Nat Mater. 2025. PMID: 39843682
Neoadjuvant Chemotherapy for Newly Diagnosed, Advanced Ovarian Cancer: ASCO Guideline Update.
Gaillard S, Lacchetti C, Armstrong DK, Cliby WA, Edelson MI, Garcia AA, Ghebre RG, Gressel GM, Lesnock JL, Meyer LA, Moore KN, O'Cearbhaill RE, Olawaiye AB, Salani R, Sparacio D, van Driel WJ, Tew WP. Gaillard S, et al. Among authors: garcia aa. J Clin Oncol. 2025 Jan 22:JCO2402589. doi: 10.1200/JCO-24-02589. Online ahead of print. J Clin Oncol. 2025. PMID: 39841949
Life satisfaction around the world: Measurement invariance of the Satisfaction With Life Scale (SWLS) across 65 nations, 40 languages, gender identities, and age groups.
Swami V, Stieger S, Voracek M, Aavik T, Abdollahpour Ranjbar H, Adebayo SO, Afhami R, Ahmed O, Aimé A, Akel M, Al Halbusi H, Alexias G, Ali KF, Alp-Dal N, Alsalhani AB, Álvarez-Solas S, Amaral ACS, Andrianto S, Aspden T, Argyrides M, Aruta JJBR, Atkin S, Ayandele O, Baceviciene M, Bahbouh R, Ballesio A, Barron D, Bellard A, Bender SS, Beydaǧ KD, Birovljević G, Blackburn MÈ, Borja-Alvarez T, Borowiec J, Bozogáňová M, Bratland-Sanda S, Browning MHEM, Brytek-Matera A, Burakova M, Çakır-Koçak Y, Camacho P, Camilleri VE, Cazzato V, Cerea S, Chaiwutikornwanich A, Chaleeraktrakoon T, Chambers T, Chen QW, Chen X, Chien CL, Chobthamkit P, Choompunuch B, Compte EJ, Corrigan J, Cosmas G, Cowden RG, Czepczor-Bernat K, Czub M, da Silva WR, Dadfar M, Dalley SE, Dany L, Datu JAD, de Carvalho PHB, Coelho GLH, De Jesus AOS, Debbabi SH, Dhakal S, Di Bernardo F, Dimitrova DD, Dion J, Dixson B, Donofrio SM, Drysch M, Du H, Dzhambov AM, El-Jor C, Enea V, Eskin M, Farbod F, Farrugia L, Fian L, Fisher ML, Folwarczny M, Frederick DA, Fuller-Tyszkiewicz M, Furnham A, García AA, Geller S, Ghisi M, Ghorbani A, Gomez Martinez MA, Gradidge S, Graf S, Grano C, Gyene G, Hallit S, Hamdan M, Handelzalts JE… See abstract for full author list ➔ Swami V, et al. Among authors: garcia aa. PLoS One. 2025 Jan 22;20(1):e0313107. doi: 10.1371/journal.pone.0313107. eCollection 2025. PLoS One. 2025. PMID: 39841629 Free article.
8,572 results