Wrighton C - Search Results

1

Size-dependent effects of nanoparticles on the activity of cytochrome P450 isoenzymes.

Fröhlich E, Kueznik T, Samberger C, Roblegg E, Wrighton C, Pieber TR. Fröhlich E, et al. Among authors: wrighton c. Toxicol Appl Pharmacol. 2010 Feb 1;242(3):326-32. doi: 10.1016/j.taap.2009.11.002. Epub 2009 Nov 10. Toxicol Appl Pharmacol. 2010. PMID: 19909766

2

Prediction of glucose concentration in post-cardiothoracic surgery patients using continuous glucose monitoring.

Schaupp L, Plank J, Köhler G, Schaller R, Wrighton C, Ellmerer M, Pieber TR. Schaupp L, et al. Among authors: wrighton c. Diabetes Technol Ther. 2011 Feb;13(2):127-34. doi: 10.1089/dia.2010.0117. Diabetes Technol Ther. 2011. PMID: 21284479 Clinical Trial.

3

Lipid-heparin infusion suppresses the IL-10 response to trauma in subcutaneous adipose tissue in humans.

Ikeoka DT, Pachler C, Mader JK, Bock G, Neves AL, Svehlikova E, Feichtner F, Koehler G, Wrighton CJ, Pieber TR, Ellmerer M. Ikeoka DT, et al. Among authors: wrighton cj. Obesity (Silver Spring). 2011 Apr;19(4):715-21. doi: 10.1038/oby.2010.227. Epub 2010 Nov 18. Obesity (Silver Spring). 2011. PMID: 21088675 Free article. Clinical Trial.

4

Kinetic and structural characterisation of Escherichia coli nitroreductase mutants showing improved efficacy for the prodrug substrate CB1954.

Race PR, Lovering AL, White SA, Grove JI, Searle PF, Wrighton CW, Hyde EI. Race PR, et al. Among authors: wrighton cw. J Mol Biol. 2007 Apr 27;368(2):481-92. doi: 10.1016/j.jmb.2007.02.012. Epub 2007 Feb 11. J Mol Biol. 2007. PMID: 17350040

5

Transcriptionally targeted nonviral gene transfer using a beta-catenin/TCF-dependent promoter in a series of different human low passage colon cancer cells.

Gaedtke L, Pelisek J, Lipinski KS, Wrighton CJ, Wagner E. Gaedtke L, et al. Among authors: wrighton cj. Mol Pharm. 2007 Jan-Feb;4(1):129-39. doi: 10.1021/mp0600586. Mol Pharm. 2007. PMID: 17274670

6

Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.

Race PR, Lovering AL, Green RM, Ossor A, White SA, Searle PF, Wrighton CJ, Hyde EI. Race PR, et al. Among authors: wrighton cj. J Biol Chem. 2005 Apr 8;280(14):13256-64. doi: 10.1074/jbc.M409652200. Epub 2005 Jan 31. J Biol Chem. 2005. PMID: 15684426 Free article.

7

Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70.

Djeha HA, Todryk SM, Pelech S, Wrighton CJ, Irvine AS, Mountain A, Lipinski KS. Djeha HA, et al. Among authors: wrighton cj. Cancer Gene Ther. 2005 Jun;12(6):560-71. doi: 10.1038/sj.cgt.7700807. Cancer Gene Ther. 2005. PMID: 15665820

8

Optimization of a synthetic beta-catenin-dependent promoter for tumor-specific cancer gene therapy.

Lipinski KS, Djeha HA, Gawn J, Cliffe S, Maitland NJ, Palmer DH, Mountain A, Irvine AS, Wrighton CJ. Lipinski KS, et al. Among authors: wrighton cj. Mol Ther. 2004 Jul;10(1):150-61. doi: 10.1016/j.ymthe.2004.03.021. Mol Ther. 2004. PMID: 15233950 Free article.

9

An oncolytic adenovirus vector combining enhanced cell-to-cell spreading, mediated by the ADP cytolytic protein, with selective replication in cancer cells with deregulated wnt signaling.

Toth K, Djeha H, Ying B, Tollefson AE, Kuppuswamy M, Doronin K, Krajcsi P, Lipinski K, Wrighton CJ, Wold WS. Toth K, et al. Among authors: wrighton cj. Cancer Res. 2004 May 15;64(10):3638-44. doi: 10.1158/0008-5472.CAN-03-3882. Cancer Res. 2004. PMID: 15150123

10

Generation of Escherichia coli nitroreductase mutants conferring improved cell sensitization to the prodrug CB1954.

Grove JI, Lovering AL, Guise C, Race PR, Wrighton CJ, White SA, Hyde EI, Searle PF. Grove JI, et al. Among authors: wrighton cj. Cancer Res. 2003 Sep 1;63(17):5532-7. Cancer Res. 2003. PMID: 14500391

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