Xu B - Search Results

1

Triptolide simultaneously induces reactive oxygen species, inhibits NF-kappaB activity and sensitizes 5-fluorouracil in colorectal cancer cell lines.

Xu B, Guo X, Mathew S, Armesilla AL, Cassidy J, Darling JL, Wang W. Xu B, et al. Cancer Lett. 2010 May 28;291(2):200-8. doi: 10.1016/j.canlet.2009.10.013. Epub 2009 Nov 10. Cancer Lett. 2010. PMID: 19903580

2

Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines.

Guo X, Xu B, Pandey S, Goessl E, Brown J, Armesilla AL, Darling JL, Wang W. Guo X, et al. Among authors: xu b. Cancer Lett. 2010 Apr 1;290(1):104-13. doi: 10.1016/j.canlet.2009.09.002. Epub 2009 Sep 25. Cancer Lett. 2010. PMID: 19782464

3

Triptolide, a Chinese herbal extract, enhances drug sensitivity of resistant myeloid leukemia cell lines through downregulation of HIF-1α and Nrf2.

Chen F, Liu Y, Wang S, Guo X, Shi P, Wang W, Xu B. Chen F, et al. Among authors: xu b. Pharmacogenomics. 2013 Aug;14(11):1305-17. doi: 10.2217/pgs.13.122. Pharmacogenomics. 2013. PMID: 23930677

4

Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition.

Zha J, Chen F, Dong H, Shi P, Yao Y, Zhang Y, Li R, Wang S, Li P, Wang W, Xu B. Zha J, et al. Among authors: xu b. J Transl Med. 2014 Jun 11;12:163. doi: 10.1186/1479-5876-12-163. J Transl Med. 2014. PMID: 24915933 Free PMC article.

5

A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor.

Li Y, Chen K, Zhou Y, Xiao Y, Deng M, Jiang Z, Ye W, Wang X, Wei X, Li J, Liang J, Zheng Z, Yao Y, Wang W, Li P, Xu B. Li Y, et al. Among authors: xu b. Curr Cancer Drug Targets. 2015;15(6):493-503. doi: 10.2174/156800961506150805153230. Curr Cancer Drug Targets. 2015. PMID: 26282548

6

Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models.

Deng M, Jiang Z, Li Y, Zhou Y, Li J, Wang X, Yao Y, Wang W, Li P, Xu B. Deng M, et al. Among authors: xu b. Oncotarget. 2016 Dec 13;7(50):82200-82212. doi: 10.18632/oncotarget.9413. Oncotarget. 2016. PMID: 27203215 Free PMC article.

7

Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption.

Zhao H, Shi P, Deng M, Jiang Z, Li Y, Kannappan V, Wang W, Li P, Xu B. Zhao H, et al. Among authors: xu b. Oncotarget. 2016 Dec 20;7(51):85515-85528. doi: 10.18632/oncotarget.13454. Oncotarget. 2016. PMID: 27888802 Free PMC article.

8

Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2.

Xu B, Wang S, Li R, Chen K, He L, Deng M, Kannappan V, Zha J, Dong H, Wang W. Xu B, et al. Cell Death Dis. 2017 May 18;8(5):e2797. doi: 10.1038/cddis.2017.176. Cell Death Dis. 2017. PMID: 28518151 Free PMC article.

9

Simultaneous detection of MDR1 and WT1 gene expression to predict the prognosis of adult acute lymphoblastic leukemia.

Xu B, Song X, Yip NC, Xiao P, Zhang Y, Wang W, Zhou S. Xu B, et al. Hematology. 2010 Apr;15(2):74-80. doi: 10.1179/102453310X12583347009937. Hematology. 2010. PMID: 20423567 Free article. Clinical Trial.

10

Disulfiram/copper complex activated JNK/c-jun pathway and sensitized cytotoxicity of doxorubicin in doxorubicin resistant leukemia HL60 cells.

Xu B, Shi P, Fombon IS, Zhang Y, Huang F, Wang W, Zhou S. Xu B, et al. Blood Cells Mol Dis. 2011 Dec 15;47(4):264-9. doi: 10.1016/j.bcmd.2011.08.004. Epub 2011 Sep 10. Blood Cells Mol Dis. 2011. PMID: 21911303

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