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In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of receptors' down-regulation and dimers' disruption.
Larbouret C, Gaborit N, Chardès T, Coelho M, Campigna E, Bascoul-Mollevi C, Mach JP, Azria D, Robert B, Pèlegrin A. Larbouret C, et al. Among authors: robert b. Neoplasia. 2012 Feb;14(2):121-30. doi: 10.1593/neo.111602. Neoplasia. 2012. PMID: 22431920 Free PMC article.
Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the "THERAPY"phase 1-2 trial.
Assenat E, Azria D, Mollevi C, Guimbaud R, Tubiana-Mathieu N, Smith D, Delord JP, Samalin E, Portales F, Larbouret C, Robert B, Bibeau F, Bleuse JP, Crapez E, Ychou M, Pèlegrin A. Assenat E, et al. Among authors: robert b. Oncotarget. 2015 May 20;6(14):12796-808. doi: 10.18632/oncotarget.3473. Oncotarget. 2015. PMID: 25918250 Free PMC article. Clinical Trial.
[Bispecific antibodies: what future?].
Pèlegrin A, Robert B. Pèlegrin A, et al. Among authors: robert b. Med Sci (Paris). 2009 Dec;25(12):1155-8. doi: 10.1051/medsci/200925121155. Med Sci (Paris). 2009. PMID: 20035697 Free article. Review. French.
Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice.
Ladjemi MZ, Chardes T, Corgnac S, Garambois V, Morisseau S, Robert B, Bascoul-Mollevi C, Ait Arsa I, Jacot W, Pouget JP, Pelegrin A, Navarro-Teulon I. Ladjemi MZ, et al. Among authors: robert b. Breast Cancer Res. 2011 Feb 4;13(1):R17. doi: 10.1186/bcr2826. Breast Cancer Res. 2011. PMID: 21294885 Free PMC article.
610 results