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Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK.
Krysov S, Steele AJ, Coelho V, Linley A, Sanchez Hidalgo M, Carter M, Potter KN, Kennedy B, Duncombe AS, Ashton-Key M, Forconi F, Stevenson FK, Packham G. Krysov S, et al. Among authors: potter kn. Blood. 2014 Nov 13;124(20):3101-9. doi: 10.1182/blood-2014-04-567198. Epub 2014 Aug 28. Blood. 2014. PMID: 25170122 Free PMC article.
High surface IgM levels associate with shorter response to ibrutinib and BTK bypass in patients with CLL.
Chiodin G, Drennan S, Martino EA, Ondrisova L, Henderson I, Del Rio L, Tracy I, D'Avola A, Parker H, Bonfiglio S, Scarfò L, Sutton LA, Strefford JC, Forster J, Brake O, Potter KN, Sale B, Lanham S, Mraz M, Ghia P, Stevenson FK, Forconi F. Chiodin G, et al. Among authors: potter kn. Blood Adv. 2022 Sep 27;6(18):5494-5504. doi: 10.1182/bloodadvances.2021006659. Blood Adv. 2022. PMID: 35640238 Free PMC article.
52 results