Bhat BM - Search Results

1

(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: a wingless beta-catenin agonist that increases bone formation rate.

Pelletier JC, Lundquist JT 4th, Gilbert AM, Alon N, Bex FJ, Bhat BM, Bursavich MG, Coleburn VE, Felix LA, Green DM, Green P, Hauze DB, Kharode YP, Lam HS, Lockhead SR, Magolda RL, Matteo JJ, Mehlmann JF, Milligan C, Murrills RJ, Pirrello J, Selim S, Sharp MC, Unwalla RJ, Vera MD, Wrobel JE, Yaworsky P, Bodine PV. Pelletier JC, et al. Among authors: bhat bm. J Med Chem. 2009 Nov 26;52(22):6962-5. doi: 10.1021/jm9014197. J Med Chem. 2009. PMID: 19856966

2

Hit to lead studies on (hetero)arylpyrimidines--agonists of the canonical Wnt-beta-catenin cellular messaging system.

Gilbert AM, Bursavich MG, Alon N, Bhat BM, Bex FJ, Cain M, Coleburn V, Gironda V, Green P, Hauze DB, Kharode Y, Krishnamurthy G, Kirisits M, Lam HS, Liu YB, Lombardi S, Matteo J, Murrills R, Robinson JA, Selim S, Sharp M, Unwalla R, Varadarajan U, Zhao W, Yaworsky PJ. Gilbert AM, et al. Among authors: bhat bm. Bioorg Med Chem Lett. 2010 Jan 1;20(1):366-70. doi: 10.1016/j.bmcl.2009.10.093. Epub 2009 Oct 25. Bioorg Med Chem Lett. 2010. PMID: 19897365

3

Evidence of in vivo osteoinduction in adult rat bone by adeno-Runx2 intra-femoral delivery.

Bhat BM, Robinson JA, Coleburn VE, Zhao W, Kharode Y. Bhat BM, et al. J Cell Biochem. 2008 Apr 15;103(6):1912-24. doi: 10.1002/jcb.21581. J Cell Biochem. 2008. PMID: 17985363

4

Parathyroid hormone synergizes with non-cyclic AMP pathways to activate the cyclic AMP response element.

Murrills RJ, Andrews JL, Samuel RL, Coleburn VE, Bhat BM, Bhat RA, Bex FJ, Bodine PV. Murrills RJ, et al. Among authors: bhat bm. J Cell Biochem. 2009 Apr 1;106(5):887-95. doi: 10.1002/jcb.22057. J Cell Biochem. 2009. PMID: 19180574

5

Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling.

Bhat BM, Allen KM, Liu W, Graham J, Morales A, Anisowicz A, Lam HS, McCauley C, Coleburn V, Cain M, Fortier E, Bhat RA, Bex FJ, Yaworsky PJ. Bhat BM, et al. Gene. 2007 Apr 15;391(1-2):103-12. doi: 10.1016/j.gene.2006.12.014. Epub 2006 Dec 29. Gene. 2007. PMID: 17276019

6

A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V).

Murrills RJ, Matteo JJ, Bhat BM, Coleburn VE, Allen KM, Chen W, Damagnez V, Bhat RA, Bex FJ, Bodine PV. Murrills RJ, et al. Among authors: bhat bm. J Cell Biochem. 2009 Dec 1;108(5):1066-75. doi: 10.1002/jcb.22335. J Cell Biochem. 2009. PMID: 19746449

7

In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity.

Murrills RJ, Matteo JJ, Samuel RL, Andrews JL, Bhat BM, Coleburn VE, Kharode YP, Bex FJ. Murrills RJ, et al. Among authors: bhat bm. Bone. 2004 Dec;35(6):1263-72. doi: 10.1016/j.bone.2004.08.015. Bone. 2004. PMID: 15589208

8

High bone mass in mice expressing a mutant LRP5 gene.

Babij P, Zhao W, Small C, Kharode Y, Yaworsky PJ, Bouxsein ML, Reddy PS, Bodine PV, Robinson JA, Bhat B, Marzolf J, Moran RA, Bex F. Babij P, et al. J Bone Miner Res. 2003 Jun;18(6):960-74. doi: 10.1359/jbmr.2003.18.6.960. J Bone Miner Res. 2003. PMID: 12817748 Free article.

9

Isogenic human cell lines for drug discovery: regulation of target gene expression by engineered zinc-finger protein transcription factors.

Liu PQ, Tan S, Mendel MC, Murrills RJ, Bhat BM, Schlag B, Samuel R, Matteo JJ, de la Rosa R, Howes K, Reik A, Case CC, Bex FJ, Young K, Gregory PD. Liu PQ, et al. Among authors: bhat bm. J Biomol Screen. 2005 Jun;10(4):304-13. doi: 10.1177/1087057104272663. J Biomol Screen. 2005. PMID: 15964931

10

Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts.

Pratap J, Galindo M, Zaidi SK, Vradii D, Bhat BM, Robinson JA, Choi JY, Komori T, Stein JL, Lian JB, Stein GS, van Wijnen AJ. Pratap J, et al. Among authors: bhat bm. Cancer Res. 2003 Sep 1;63(17):5357-62. Cancer Res. 2003. PMID: 14500368

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