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168 results

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Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK.
Sambade MJ, Camp JT, Kimple RJ, Sartor CI, Shields JM. Sambade MJ, et al. Among authors: kimple rj. Radiother Oncol. 2009 Dec;93(3):639-44. doi: 10.1016/j.radonc.2009.09.006. Epub 2009 Oct 23. Radiother Oncol. 2009. PMID: 19853943 Free PMC article.
Targeted inhibition of BET proteins in HPV16-positive head and neck squamous cell carcinoma reveals heterogeneous transcriptional responses.
Rao A, Stosic MS, Mohanty C, Suresh D, Wang AR, Lee DL, Nickel KP, Chandrashekar DS, Kimple RJ, Lambert PF, Kendziorski C, Rounge TB, Iyer G. Rao A, et al. Among authors: kimple rj. Front Oncol. 2024 Sep 5;14:1440836. doi: 10.3389/fonc.2024.1440836. eCollection 2024. Front Oncol. 2024. PMID: 39301555 Free PMC article.
Cancer therapy-related salivary dysfunction.
Paz C, Glassey A, Frick A, Sattar S, Zaorsky NG, Blitzer GC, Kimple RJ. Paz C, et al. Among authors: kimple rj. J Clin Invest. 2024 Sep 3;134(17):e182661. doi: 10.1172/JCI182661. J Clin Invest. 2024. PMID: 39225092 Free PMC article. Review.
Multidisciplinary Management of Advanced Thyroid Cancer.
Bruce JY, Glazer TA, Kimple RJ. Bruce JY, et al. Among authors: kimple rj. JCO Oncol Pract. 2024 Jul;20(7):877-878. doi: 10.1200/OP.24.00283. Epub 2024 Mar 29. JCO Oncol Pract. 2024. PMID: 38810182 Free PMC article.
Development of an Engineered Single-Domain Antibody for Targeting MET in Non-Small Cell Lung Cancer.
Luo NY, Minne RL, Gallant JP, Gunaratne GS, West JL, Javeri S, Robertson AJ, Lake EW, Engle JW, Mixdorf JC, Aluicio-Sarduy E, Nickel KP, Hernandez R, Kimple RJ, Baschnagel AM, LeBeau AM. Luo NY, et al. Among authors: kimple rj. Bioconjug Chem. 2024 Mar 20;35(3):389-399. doi: 10.1021/acs.bioconjchem.4c00019. Epub 2024 Mar 12. Bioconjug Chem. 2024. PMID: 38470611
Morphologic Spectrum of HPV-associated Sinonasal Carcinomas.
Abi-Saab T, Lozar T, Chen Y, Tannenbaum AP, Geye H, Yu M, Weisman P, Harari PM, Kimple RJ, Lambert PF, Lloyd RV, Hu R. Abi-Saab T, et al. Among authors: kimple rj. Head Neck Pathol. 2024 Aug 5;18(1):67. doi: 10.1007/s12105-024-01670-1. Head Neck Pathol. 2024. PMID: 39101976
A Phase 2 Randomized Clinical Trial Evaluating 4-Dimensional Computed Tomography Ventilation-Based Functional Lung Avoidance Radiation Therapy for Non-Small Cell Lung Cancer.
Baschnagel AM, Flakus MJ, Wallat EM, Wuschner AE, Chappell RJ, Bayliss RA, Kimple RJ, Christensen GE, Reinhardt JM, Bassetti MF, Bayouth JE. Baschnagel AM, et al. Among authors: kimple rj. Int J Radiat Oncol Biol Phys. 2024 Aug 1;119(5):1393-1402. doi: 10.1016/j.ijrobp.2024.02.019. Epub 2024 Feb 20. Int J Radiat Oncol Biol Phys. 2024. PMID: 38387810 Clinical Trial.
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