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Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis.
Lin Y, Ritchea S, Logar A, Slight S, Messmer M, Rangel-Moreno J, Guglani L, Alcorn JF, Strawbridge H, Park SM, Onishi R, Nyugen N, Walter MJ, Pociask D, Randall TD, Gaffen SL, Iwakura Y, Kolls JK, Khader SA. Lin Y, et al. Among authors: iwakura y. Immunity. 2009 Nov 20;31(5):799-810. doi: 10.1016/j.immuni.2009.08.025. Epub 2009 Oct 22. Immunity. 2009. PMID: 19853481 Free PMC article.
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia.
Aujla SJ, Chan YR, Zheng M, Fei M, Askew DJ, Pociask DA, Reinhart TA, McAllister F, Edeal J, Gaus K, Husain S, Kreindler JL, Dubin PJ, Pilewski JM, Myerburg MM, Mason CA, Iwakura Y, Kolls JK. Aujla SJ, et al. Among authors: iwakura y. Nat Med. 2008 Mar;14(3):275-81. doi: 10.1038/nm1710. Epub 2008 Feb 10. Nat Med. 2008. PMID: 18264110 Free PMC article.
TNF-alpha from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection.
Fei M, Bhatia S, Oriss TB, Yarlagadda M, Khare A, Akira S, Saijo S, Iwakura Y, Fallert Junecko BA, Reinhart TA, Foreman O, Ray P, Kolls J, Ray A. Fei M, et al. Among authors: iwakura y. Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5360-5. doi: 10.1073/pnas.1015476108. Epub 2011 Mar 14. Proc Natl Acad Sci U S A. 2011. PMID: 21402950 Free PMC article.
Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans.
Saijo S, Ikeda S, Yamabe K, Kakuta S, Ishigame H, Akitsu A, Fujikado N, Kusaka T, Kubo S, Chung SH, Komatsu R, Miura N, Adachi Y, Ohno N, Shibuya K, Yamamoto N, Kawakami K, Yamasaki S, Saito T, Akira S, Iwakura Y. Saijo S, et al. Among authors: iwakura y. Immunity. 2010 May 28;32(5):681-91. doi: 10.1016/j.immuni.2010.05.001. Epub 2010 May 20. Immunity. 2010. PMID: 20493731 Free article.
795 results