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1,292 results

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Identification of orally-bioavailable antagonists of the TRPV4 ion-channel.
Wei ZL, Nguyen MT, O'Mahony DJ, Acevedo A, Zipfel S, Zhang Q, Liu L, Dourado M, Chi C, Yip V, DeFalco J, Gustafson A, Emerling DE, Kelly MG, Kincaid J, Vincent F, Duncton MA. Wei ZL, et al. Among authors: nguyen mt. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. doi: 10.1016/j.bmcl.2015.06.098. Epub 2015 Jul 6. Bioorg Med Chem Lett. 2015. PMID: 26235950
Identification and characterization of novel TRPV4 modulators.
Vincent F, Acevedo A, Nguyen MT, Dourado M, DeFalco J, Gustafson A, Spiro P, Emerling DE, Kelly MG, Duncton MA. Vincent F, et al. Among authors: nguyen mt. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4. doi: 10.1016/j.bbrc.2009.09.007. Epub 2009 Sep 6. Biochem Biophys Res Commun. 2009. PMID: 19737537
Novel 5-azaindole factor VIIa inhibitors.
Riggs JR, Hu H, Kolesnikov A, Leahy EM, Wesson KE, Shrader WD, Vijaykumar D, Wahl TA, Tong Z, Sprengeler PA, Green MJ, Yu C, Katz BA, Sanford E, Nguyen M, Cabuslay R, Young WB. Riggs JR, et al. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3197-200. doi: 10.1016/j.bmcl.2006.03.049. Epub 2006 Apr 18. Bioorg Med Chem Lett. 2006. PMID: 16621549
Potent 4-amino-5-azaindole factor VIIa inhibitors.
Hu H, Kolesnikov A, Riggs JR, Wesson KE, Stephens R, Leahy EM, Shrader WD, Sprengeler PA, Green MJ, Sanford E, Nguyen M, Gjerstad E, Cabuslay R, Young WB. Hu H, et al. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4567-70. doi: 10.1016/j.bmcl.2006.06.016. Epub 2006 Jun 21. Bioorg Med Chem Lett. 2006. PMID: 16793264
Novel, potent, selective, and orally bioavailable human betaII-tryptase inhibitors.
Sperandio D, Tai VW, Lohman J, Hirschbein B, Mendonca R, Lee CS, Spencer JR, Janc J, Nguyen M, Beltman J, Sprengeler P, Scheerens H, Lin T, Liu L, Gadre A, Kellogg A, Green MJ, McGrath ME. Sperandio D, et al. Bioorg Med Chem Lett. 2006 Aug 1;16(15):4085-9. doi: 10.1016/j.bmcl.2006.04.088. Epub 2006 May 24. Bioorg Med Chem Lett. 2006. PMID: 16725321
Expression and characterization of recombinant gamma-tryptase.
Yuan J, Beltman J, Gjerstad E, Nguyen MT, Sampang J, Chan H, Janc JW, Clark JM. Yuan J, et al. Among authors: nguyen mt. Protein Expr Purif. 2006 Sep;49(1):47-54. doi: 10.1016/j.pep.2006.04.018. Epub 2006 May 23. Protein Expr Purif. 2006. PMID: 16815034
Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index.
Desnoyers LR, Vasiljeva O, Richardson JH, Yang A, Menendez EE, Liang TW, Wong C, Bessette PH, Kamath K, Moore SJ, Sagert JG, Hostetter DR, Han F, Gee J, Flandez J, Markham K, Nguyen M, Krimm M, Wong KR, Liu S, Daugherty PS, West JW, Lowman HB. Desnoyers LR, et al. Sci Transl Med. 2013 Oct 16;5(207):207ra144. doi: 10.1126/scitranslmed.3006682. Sci Transl Med. 2013. PMID: 24132639
1,292 results