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Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770.
Van Goor F, Hadida S, Grootenhuis PD, Burton B, Cao D, Neuberger T, Turnbull A, Singh A, Joubran J, Hazlewood A, Zhou J, McCartney J, Arumugam V, Decker C, Yang J, Young C, Olson ER, Wine JJ, Frizzell RA, Ashlock M, Negulescu P. Van Goor F, et al. Among authors: wine jj. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18825-30. doi: 10.1073/pnas.0904709106. Epub 2009 Oct 21. Proc Natl Acad Sci U S A. 2009. PMID: 19846789 Free PMC article.
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.
Van Goor F, Hadida S, Grootenhuis PD, Burton B, Stack JH, Straley KS, Decker CJ, Miller M, McCartney J, Olson ER, Wine JJ, Frizzell RA, Ashlock M, Negulescu PA. Van Goor F, et al. Among authors: wine jj. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18843-8. doi: 10.1073/pnas.1105787108. Epub 2011 Oct 5. Proc Natl Acad Sci U S A. 2011. PMID: 21976485 Free PMC article.
High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia.
Vaidyanathan S, Salahudeen AA, Sellers ZM, Bravo DT, Choi SS, Batish A, Le W, Baik R, de la O S, Kaushik MP, Galper N, Lee CM, Teran CA, Yoo JH, Bao G, Chang EH, Patel ZM, Hwang PH, Wine JJ, Milla CE, Desai TJ, Nayak JV, Kuo CJ, Porteus MH. Vaidyanathan S, et al. Among authors: wine jj. Cell Stem Cell. 2020 Feb 6;26(2):161-171.e4. doi: 10.1016/j.stem.2019.11.002. Epub 2019 Dec 12. Cell Stem Cell. 2020. PMID: 31839569 Free PMC article.
CFTR and other Cl- channels in human airway cells.
Wine JJ, Finkbeiner WE, Haws C, Krouse ME, Moon S, Widdicombe JH, Xia Y. Wine JJ, et al. Jpn J Physiol. 1994;44 Suppl 2:S199-205. Jpn J Physiol. 1994. PMID: 7752526
144 results