Nassr N - Search Results

1

Effects of rifampicin on the pharmacokinetics of roflumilast and roflumilast N-oxide in healthy subjects.

Nassr N, Huennemeyer A, Herzog R, von Richter O, Hermann R, Koch M, Duffy K, Zech K, Lahu G. Nassr N, et al. Br J Clin Pharmacol. 2009 Oct;68(4):580-7. doi: 10.1111/j.1365-2125.2009.03478.x. Br J Clin Pharmacol. 2009. PMID: 19843061 Free PMC article.

2

Lack of a pharmacokinetic interaction between steady-state roflumilast and single-dose midazolam in healthy subjects.

Nassr N, Lahu G, von Richter O, Reutter F, Knoerzer D, Zech K, Erb KA, Schug B, Blume H, Hermann R. Nassr N, et al. Br J Clin Pharmacol. 2007 Mar;63(3):365-70. doi: 10.1111/j.1365-2125.2006.02762.x. Epub 2006 Sep 29. Br J Clin Pharmacol. 2007. PMID: 16981901 Free PMC article. Clinical Trial.

3

Magnesium hydroxide/aluminium hydroxide-containing antacid does not affect the pharmacokinetics of the targeted phosphodiesterase 4 inhibitor roflumilast.

Nassr N, Lahu G, Hünnemeyer A, von Richter O, Knoerzer D, Reutter F, Zech K, Hermann R. Nassr N, et al. J Clin Pharmacol. 2007 May;47(5):660-6. doi: 10.1177/0091270006297920. Epub 2007 Mar 20. J Clin Pharmacol. 2007. PMID: 17374735 Clinical Trial. No abstract available.

4

Steady-state pharmacokinetics of roflumilast and roflumilast N-oxide in patients with mild and moderate liver cirrhosis.

Hermann R, Nassr N, Lahu G, Péterfai E, Knoerzer D, Herzog R, Zech K, de Mey C. Hermann R, et al. Among authors: nassr n. Clin Pharmacokinet. 2007;46(5):403-16. doi: 10.2165/00003088-200746050-00003. Clin Pharmacokinet. 2007. PMID: 17465639 Clinical Trial.

5

The targeted oral, once-daily phosphodiesterase 4 inhibitor roflumilast and the leukotriene receptor antagonist montelukast do not exhibit significant pharmacokinetic interactions.

Böhmer GM, Nassr N, Wenger M, Hünnemeyer A, Lahu G, Templin S, Gleiter CH, Hermann R. Böhmer GM, et al. Among authors: nassr n. J Clin Pharmacol. 2009 Apr;49(4):389-97. doi: 10.1177/0091270008330980. J Clin Pharmacol. 2009. PMID: 19318692 Clinical Trial.

6

Effect of steady-state enoxacin on single-dose pharmacokinetics of roflumilast and roflumilast N-oxide.

Lahu G, Nassr N, Herzog R, Elmlinger M, Ruth P, Hinder M, Huennemeyer A. Lahu G, et al. Among authors: nassr n. J Clin Pharmacol. 2011 Apr;51(4):586-93. doi: 10.1177/0091270010370590. Epub 2010 May 13. J Clin Pharmacol. 2011. PMID: 20466871 Clinical Trial.

7

No dose adjustment on coadministration of the PDE4 inhibitor roflumilast with a weak CYP3A, CYP1A2, and CYP2C19 inhibitor: an investigation using cimetidine.

Böhmer GM, Gleiter CH, Mörike K, Nassr N, Walz A, Lahu G. Böhmer GM, et al. Among authors: nassr n. J Clin Pharmacol. 2011 Apr;51(4):594-602. doi: 10.1177/0091270010368282. Epub 2010 May 19. J Clin Pharmacol. 2011. PMID: 20484614

8

Absence of pharmacokinetic interaction between roflumilast and digoxin in healthy adults.

Eckermann G, Lahu G, Nassr N, Bethke TD. Eckermann G, et al. Among authors: nassr n. J Clin Pharmacol. 2012 Feb;52(2):251-7. doi: 10.1177/0091270010389467. J Clin Pharmacol. 2012. PMID: 21257799 Clinical Trial.

9

Supra-therapeutic doses of roflumilast have no effect on cardiac repolarization in healthy subjects.

Huennemeyer A, Nassr N, Bredenbröker D, Lahu G. Huennemeyer A, et al. Among authors: nassr n. Expert Opin Drug Saf. 2011 Jul;10(4):509-19. doi: 10.1517/14740338.2011.581659. Epub 2011 May 17. Expert Opin Drug Saf. 2011. PMID: 21585288 Clinical Trial.

10

No relevant cardiac, pharmacokinetic or safety interactions between roflumilast and inhaled formoterol in healthy subjects: an open-label, randomised, actively controlled study.

de Mey C, Nassr N, Lahu G. de Mey C, et al. Among authors: nassr n. BMC Clin Pharmacol. 2011 Jun 1;11:7. doi: 10.1186/1472-6904-11-7. BMC Clin Pharmacol. 2011. PMID: 21631929 Free PMC article. Clinical Trial.

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