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408 results

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K-ras mutation targeted to gastric tissue progenitor cells results in chronic inflammation, an altered microenvironment, and progression to intraepithelial neoplasia.
Okumura T, Ericksen RE, Takaishi S, Wang SS, Dubeykovskiy Z, Shibata W, Betz KS, Muthupalani S, Rogers AB, Fox JG, Rustgi AK, Wang TC. Okumura T, et al. Among authors: rustgi ak. Cancer Res. 2010 Nov 1;70(21):8435-45. doi: 10.1158/0008-5472.CAN-10-1506. Epub 2010 Oct 19. Cancer Res. 2010. PMID: 20959488 Free PMC article.
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration.
Giroux V, Lento AA, Islam M, Pitarresi JR, Kharbanda A, Hamilton KE, Whelan KA, Long A, Rhoades B, Tang Q, Nakagawa H, Lengner CJ, Bass AJ, Wileyto EP, Klein-Szanto AJ, Wang TC, Rustgi AK. Giroux V, et al. Among authors: rustgi ak. J Clin Invest. 2017 Jun 1;127(6):2378-2391. doi: 10.1172/JCI88941. Epub 2017 May 8. J Clin Invest. 2017. PMID: 28481227 Free PMC article.
Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.
Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, Gross S, Renz BW, Setlik W, Martinez AN, Chen X, Nizami S, Lee HG, Kang HP, Caldwell JM, Asfaha S, Westphalen CB, Graham T, Jin G, Nagar K, Wang H, Kheirbek MA, Kolhe A, Carpenter J, Glaire M, Nair A, Renders S, Manieri N, Muthupalani S, Fox JG, Reichert M, Giraud AS, Schwabe RF, Pradere JP, Walton K, Prakash A, Gumucio D, Rustgi AK, Stappenbeck TS, Friedman RA, Gershon MD, Sims P, Grikscheit T, Lee FY, Karsenty G, Mukherjee S, Wang TC. Worthley DL, et al. Among authors: rustgi ak. Cell. 2015 Jan 15;160(1-2):269-84. doi: 10.1016/j.cell.2014.11.042. Cell. 2015. PMID: 25594183 Free PMC article.
Stem cells and origins of cancer in the upper gastrointestinal tract.
Hayakawa Y, Nakagawa H, Rustgi AK, Que J, Wang TC. Hayakawa Y, et al. Among authors: rustgi ak. Cell Stem Cell. 2021 Aug 5;28(8):1343-1361. doi: 10.1016/j.stem.2021.05.012. Epub 2021 Jun 14. Cell Stem Cell. 2021. PMID: 34129814 Free PMC article. Review.
Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus.
Lee Y, Urbanska AM, Hayakawa Y, Wang H, Au AS, Luna AM, Chang W, Jin G, Bhagat G, Abrams JA, Friedman RA, Varro A, Wang KK, Boyce M, Rustgi AK, Sepulveda AR, Quante M, Wang TC. Lee Y, et al. Among authors: rustgi ak. Oncotarget. 2017 Jan 3;8(1):203-214. doi: 10.18632/oncotarget.10667. Oncotarget. 2017. PMID: 27448962 Free PMC article.
Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.
Quante M, Bhagat G, Abrams JA, Marache F, Good P, Lee MD, Lee Y, Friedman R, Asfaha S, Dubeykovskaya Z, Mahmood U, Figueiredo JL, Kitajewski J, Shawber C, Lightdale CJ, Rustgi AK, Wang TC. Quante M, et al. Among authors: rustgi ak. Cancer Cell. 2012 Jan 17;21(1):36-51. doi: 10.1016/j.ccr.2011.12.004. Cancer Cell. 2012. PMID: 22264787 Free PMC article.
The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.
Kobayashi H, Gieniec KA, Lannagan TRM, Wang T, Asai N, Mizutani Y, Iida T, Ando R, Thomas EM, Sakai A, Suzuki N, Ichinose M, Wright JA, Vrbanac L, Ng JQ, Goyne J, Radford G, Lawrence MJ, Sammour T, Hayakawa Y, Klebe S, Shin AE, Asfaha S, Bettington ML, Rieder F, Arpaia N, Danino T, Butler LM, Burt AD, Leedham SJ, Rustgi AK, Mukherjee S, Takahashi M, Wang TC, Enomoto A, Woods SL, Worthley DL. Kobayashi H, et al. Among authors: rustgi ak. Gastroenterology. 2022 Mar;162(3):890-906. doi: 10.1053/j.gastro.2021.11.037. Epub 2021 Dec 6. Gastroenterology. 2022. PMID: 34883119 Free PMC article.
408 results