Patton JG - Search Results

1

A molecular basis for variation in clinical severity of isolated growth hormone deficiency type II.

Hamid R, Phillips JA 3rd, Holladay C, Cogan JD, Austin ED, Backeljauw PF, Travers SH, Patton JG. Hamid R, et al. Among authors: patton jg. J Clin Endocrinol Metab. 2009 Dec;94(12):4728-34. doi: 10.1210/jc.2009-0746. Epub 2009 Oct 16. J Clin Endocrinol Metab. 2009. PMID: 19837935 Free PMC article.

2

Disruption of exon definition produces a dominant-negative growth hormone isoform that causes somatotroph death and IGHD II.

Ryther RC, McGuinness LM, Phillips JA 3rd, Moseley CT, Magoulas CB, Robinson IC, Patton JG. Ryther RC, et al. Among authors: patton jg. Hum Genet. 2003 Jul;113(2):140-8. doi: 10.1007/s00439-003-0949-x. Epub 2003 Apr 29. Hum Genet. 2003. PMID: 12720086

3

GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allele-specific small interfering RNA (siRNA).

Ryther RC, Flynt AS, Harris BD, Phillips JA 3rd, Patton JG. Ryther RC, et al. Among authors: patton jg. Endocrinology. 2004 Jun;145(6):2988-96. doi: 10.1210/en.2003-1724. Epub 2004 Feb 26. Endocrinology. 2004. PMID: 14988388

4

siRNA therapeutics: big potential from small RNAs.

Ryther RC, Flynt AS, Phillips JA 3rd, Patton JG. Ryther RC, et al. Among authors: patton jg. Gene Ther. 2005 Jan;12(1):5-11. doi: 10.1038/sj.gt.3302356. Gene Ther. 2005. PMID: 15496962 Review.

5

Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference.

Shariat N, Ryther RC, Phillips JA 3rd, Robinson IC, Patton JG. Shariat N, et al. Among authors: patton jg. Endocrinology. 2008 Feb;149(2):580-6. doi: 10.1210/en.2007-1360. Epub 2007 Nov 15. Endocrinology. 2008. PMID: 18006625 Free PMC article.

6

Isolated growth hormone deficiency type II caused by a point mutation that alters both splice site strength and splicing enhancer function.

Shariat N, Holladay CD, Cleary RK, Phillips JA 3rd, Patton JG. Shariat N, et al. Among authors: patton jg. Clin Genet. 2008 Dec;74(6):539-45. doi: 10.1111/j.1399-0004.2008.01042.x. Epub 2008 Jun 11. Clin Genet. 2008. PMID: 18554279 Free PMC article.

7

Growth hormone deficiency and splicing fidelity: two serine/arginine-rich proteins, ASF/SF2 and SC35, act antagonistically.

Solis AS, Peng R, Crawford JB, Phillips JA 3rd, Patton JG. Solis AS, et al. Among authors: patton jg. J Biol Chem. 2008 Aug 29;283(35):23619-26. doi: 10.1074/jbc.M710175200. Epub 2008 Jun 27. J Biol Chem. 2008. PMID: 18586677 Free PMC article.

8

Splicing fidelity, enhancers, and disease.

Solis AS, Shariat N, Patton JG. Solis AS, et al. Among authors: patton jg. Front Biosci. 2008 Jan 1;13:1926-42. doi: 10.2741/2812. Front Biosci. 2008. PMID: 17981680 Review.

9

The splicing factor PSF is part of a large complex that assembles in the absence of pre-mRNA and contains all five snRNPs.

Peng R, Hawkins I, Link AJ, Patton JG. Peng R, et al. Among authors: patton jg. RNA Biol. 2006 Apr;3(2):69-76. doi: 10.4161/rna.3.2.3017. Epub 2006 Apr 9. RNA Biol. 2006. PMID: 17114945 Free article.

10

Genomic organization of zebrafish microRNAs.

Thatcher EJ, Bond J, Paydar I, Patton JG. Thatcher EJ, et al. Among authors: patton jg. BMC Genomics. 2008 May 29;9:253. doi: 10.1186/1471-2164-9-253. BMC Genomics. 2008. PMID: 18510755 Free PMC article.

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