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High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions.
Lynch C, Sakamuru S, Ooka M, Huang R, Klumpp-Thomas C, Shinn P, Gerhold D, Rossoshek A, Michael S, Casey W, Santillo MF, Fitzpatrick S, Thomas RS, Simeonov A, Xia M. Lynch C, et al. Among authors: shinn p. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:191-209. doi: 10.1146/annurev-pharmtox-112122-104310. Epub 2023 Jul 28. Annu Rev Pharmacol Toxicol. 2024. PMID: 37506331 Free PMC article. Review.
Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products.
Yasgar A, Bougie D, Eastman RT, Huang R, Itkin M, Kouznetsova J, Lynch C, McKnight C, Miller M, Ngan DK, Peryea T, Shah P, Shinn P, Xia M, Xu X, Zakharov AV, Simeonov A. Yasgar A, et al. Among authors: shinn p. ACS Pharmacol Transl Sci. 2023 Apr 14;6(5):683-701. doi: 10.1021/acsptsci.2c00194. eCollection 2023 May 12. ACS Pharmacol Transl Sci. 2023. PMID: 37200814 Free PMC article.
Fluorescence spectroscopic profiling of compound libraries.
Simeonov A, Jadhav A, Thomas CJ, Wang Y, Huang R, Southall NT, Shinn P, Smith J, Austin CP, Auld DS, Inglese J. Simeonov A, et al. Among authors: shinn p. J Med Chem. 2008 Apr 24;51(8):2363-71. doi: 10.1021/jm701301m. Epub 2008 Mar 26. J Med Chem. 2008. PMID: 18363325
Compound Management for Quantitative High-Throughput Screening.
Yasgar A, Shinn P, Jadhav A, Auld D, Michael S, Zheng W, Austin CP, Inglese J, Simeonov A. Yasgar A, et al. Among authors: shinn p. JALA Charlottesv Va. 2008 Apr;13(2):79-89. doi: 10.1016/j.jala.2007.12.004. JALA Charlottesv Va. 2008. PMID: 18496600 Free PMC article.
Monitoring compound integrity with cytochrome P450 assays and qHTS.
MacArthur R, Leister W, Veith H, Shinn P, Southall N, Austin CP, Inglese J, Auld DS. MacArthur R, et al. Among authors: shinn p. J Biomol Screen. 2009 Jun;14(5):538-46. doi: 10.1177/1087057109336954. Epub 2009 May 29. J Biomol Screen. 2009. PMID: 19483146 Free PMC article.
98 results