Broqua P - Search Results

1

WS-50030 [7-{4-[3-(1H-inden-3-yl)propyl]piperazin-1-yl}-1,3-benzoxazol-2(3H)-one]: a novel dopamine D2 receptor partial agonist/serotonin reuptake inhibitor with preclinical antipsychotic-like and antidepressant-like activity.

Brennan JA, Graf R, Grauer SM, Navarra RL, Pulicicchio CM, Hughes ZA, Lin Q, Wantuch C, Rosenzweig-Lipson S, Pruthi F, Lai M, Smith D, Goutier W, van de Neut M, Robichaud AJ, Rotella D, Feenstra RW, Kruse C, Broqua P, Beyer CE, McCreary AC, Pausch MH, Marquis KL. Brennan JA, et al. Among authors: broqua p. J Pharmacol Exp Ther. 2010 Jan;332(1):190-201. doi: 10.1124/jpet.109.157388. Epub 2009 Oct 14. J Pharmacol Exp Ther. 2010. PMID: 19828876

2

Rapid suppression of plasma testosterone levels and tumor growth in the dunning rat model treated with degarelix, a new gonadotropin-releasing hormone antagonist.

Princivalle M, Broqua P, White R, Meyer J, Mayer G, Elliott L, Bjarnason K, Haigh R, Yea C. Princivalle M, et al. Among authors: broqua p. J Pharmacol Exp Ther. 2007 Mar;320(3):1113-8. doi: 10.1124/jpet.106.112326. Epub 2006 Dec 19. J Pharmacol Exp Ther. 2007. PMID: 17179469

3

Pharmacological profile of a new, potent, and long-acting gonadotropin-releasing hormone antagonist: degarelix.

Broqua P, Riviere PJ, Conn PM, Rivier JE, Aubert ML, Junien JL. Broqua P, et al. J Pharmacol Exp Ther. 2002 Apr;301(1):95-102. doi: 10.1124/jpet.301.1.95. J Pharmacol Exp Ther. 2002. PMID: 11907162

4

GnRH antagonists: a new generation of long acting analogues incorporating p-ureido-phenylalanines at positions 5 and 6.

Jiang G, Stalewski J, Galyean R, Dykert J, Schteingart C, Broqua P, Aebi A, Aubert ML, Semple G, Robson P, Akinsanya K, Haigh R, Riviere P, Trojnar J, Junien JL, Rivier JE. Jiang G, et al. Among authors: broqua p. J Med Chem. 2001 Feb 1;44(3):453-67. doi: 10.1021/jm0003900. J Med Chem. 2001. PMID: 11462984

5

Chronic inhibition of circulating dipeptidyl peptidase IV by FE 999011 delays the occurrence of diabetes in male zucker diabetic fatty rats.

Sudre B, Broqua P, White RB, Ashworth D, Evans DM, Haigh R, Junien JL, Aubert ML. Sudre B, et al. Among authors: broqua p. Diabetes. 2002 May;51(5):1461-9. doi: 10.2337/diabetes.51.5.1461. Diabetes. 2002. PMID: 11978643

6

Evidence that the inhibition of luteinizing hormone secretion exerted by central administration of neuropeptide Y (NPY) in the rat is predominantly mediated by the NPY-Y5 receptor subtype.

Raposinho PD, Broqua P, Pierroz DD, Hayward A, Dumont Y, Quirion R, Junien JL, Aubert ML. Raposinho PD, et al. Among authors: broqua p. Endocrinology. 1999 Sep;140(9):4046-55. doi: 10.1210/endo.140.9.6985. Endocrinology. 1999. PMID: 10465275

7

Stimulation of the gonadotropic axis by the neuropeptide Y receptor Y1 antagonist/Y4 agonist 1229U91 in the male rat.

Raposinho PD, Broqua P, Hayward A, Akinsanya K, Galyean R, Schteingart C, Junien J, Aubert ML. Raposinho PD, et al. Among authors: broqua p. Neuroendocrinology. 2000 Jan;71(1):2-7. doi: 10.1159/000054514. Neuroendocrinology. 2000. PMID: 10644893

8

Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes.

Raposinho PD, Castillo E, d'Alleves V, Broqua P, Pralong FP, Aubert ML. Raposinho PD, et al. Among authors: broqua p. Endocrinology. 2000 Dec;141(12):4419-27. doi: 10.1210/endo.141.12.7842. Endocrinology. 2000. PMID: 11108250

9

Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism.

Raposinho PD, Pierroz DD, Broqua P, White RB, Pedrazzini T, Aubert ML. Raposinho PD, et al. Among authors: broqua p. Mol Cell Endocrinol. 2001 Dec 20;185(1-2):195-204. doi: 10.1016/s0303-7207(01)00620-7. Mol Cell Endocrinol. 2001. PMID: 11738809

10

Antinociceptive effects of neuropeptide Y and related peptides in mice.

Broqua P, Wettstein JG, Rocher MN, Gauthier-Martin B, Riviere PJ, Junien JL, Dahl SG. Broqua P, et al. Brain Res. 1996 Jun 10;724(1):25-32. doi: 10.1016/0006-8993(96)00262-4. Brain Res. 1996. PMID: 8816252

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