Fox J - Search Results

1

Antagonists of the calcium receptor. 2. Amino alcohol-based parathyroid hormone secretagogues.

Marquis RW, Lago AM, Callahan JF, Rahman A, Dong X, Stroup GB, Hoffman S, Gowen M, DelMar EG, Van Wagenen BC, Logan S, Shimizu S, Fox J, Nemeth EF, Roethke T, Smith BR, Ward KW, Bhatnagar P. Marquis RW, et al. Among authors: fox j. J Med Chem. 2009 Nov 12;52(21):6599-605. doi: 10.1021/jm900563e. J Med Chem. 2009. PMID: 19821575

2

Antagonists of the calcium receptor I. Amino alcohol-based parathyroid hormone secretagogues.

Marquis RW, Lago AM, Callahan JF, Trout RE, Gowen M, DelMar EG, Van Wagenen BC, Logan S, Shimizu S, Fox J, Nemeth EF, Yang Z, Roethke T, Smith BR, Ward KW, Lee J, Keenan RM, Bhatnagar P. Marquis RW, et al. Among authors: fox j. J Med Chem. 2009 Jul 9;52(13):3982-93. doi: 10.1021/jm900364m. J Med Chem. 2009. PMID: 19492813

3

An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation.

Kumar S, Matheny CJ, Hoffman SJ, Marquis RW, Schultz M, Liang X, Vasko JA, Stroup GB, Vaden VR, Haley H, Fox J, DelMar EG, Nemeth EF, Lago AM, Callahan JF, Bhatnagar P, Huffman WF, Gowen M, Yi B, Danoff TM, Fitzpatrick LA. Kumar S, et al. Among authors: fox j. Bone. 2010 Feb;46(2):534-42. doi: 10.1016/j.bone.2009.09.028. Epub 2009 Sep 26. Bone. 2010. PMID: 19786130 Clinical Trial.

4

Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats.

Gowen M, Stroup GB, Dodds RA, James IE, Votta BJ, Smith BR, Bhatnagar PK, Lago AM, Callahan JF, DelMar EG, Miller MA, Nemeth EF, Fox J. Gowen M, et al. Among authors: fox j. J Clin Invest. 2000 Jun;105(11):1595-604. doi: 10.1172/JCI9038. J Clin Invest. 2000. PMID: 10841518 Free PMC article.

5

Calcilytic compounds: potent and selective Ca2+ receptor antagonists that stimulate secretion of parathyroid hormone.

Nemeth EF, Delmar EG, Heaton WL, Miller MA, Lambert LD, Conklin RL, Gowen M, Gleason JG, Bhatnagar PK, Fox J. Nemeth EF, et al. Among authors: fox j. J Pharmacol Exp Ther. 2001 Oct;299(1):323-31. J Pharmacol Exp Ther. 2001. PMID: 11561095

6

Plasma levels of parathyroid hormone that induce anabolic effects in bone of ovariectomized rats can be achieved by stimulation of endogenous hormone secretion.

Fox J, Miller MA, Stroup GB, Nemeth EF, Miller SC. Fox J, et al. Bone. 1997 Aug;21(2):163-9. doi: 10.1016/s8756-3282(97)00108-7. Bone. 1997. PMID: 9267692

7

NPS R-568: a type II calcimimetic compound that acts on parathyroid cell calcium receptor of rats to reduce plasma levels of parathyroid hormone and calcium.

Fox J, Lowe SH, Petty BA, Nemeth EF. Fox J, et al. J Pharmacol Exp Ther. 1999 Aug;290(2):473-9. J Pharmacol Exp Ther. 1999. PMID: 10411552

8

The parathyroid calcium receptor: a novel therapeutic target for treating hyperparathyroidism.

Nemeth EF, Steffey ME, Fox J. Nemeth EF, et al. Among authors: fox j. Pediatr Nephrol. 1996 Jun;10(3):275-9. doi: 10.1007/BF00866757. Pediatr Nephrol. 1996. PMID: 8792389 Review.

9

Pharmacodynamics of the type II calcimimetic compound cinacalcet HCl.

Nemeth EF, Heaton WH, Miller M, Fox J, Balandrin MF, Van Wagenen BC, Colloton M, Karbon W, Scherrer J, Shatzen E, Rishton G, Scully S, Qi M, Harris R, Lacey D, Martin D. Nemeth EF, et al. Among authors: fox j. J Pharmacol Exp Ther. 2004 Feb;308(2):627-35. doi: 10.1124/jpet.103.057273. Epub 2003 Oct 30. J Pharmacol Exp Ther. 2004. PMID: 14593085

10

Calcimimetic compound NPS R-568 stimulates calcitonin secretion but selectively targets parathyroid gland Ca(2+) receptor in rats.

Fox J, Lowe SH, Conklin RL, Petty BA, Nemeth EF. Fox J, et al. J Pharmacol Exp Ther. 1999 Aug;290(2):480-6. J Pharmacol Exp Ther. 1999. PMID: 10411553

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