Luo J - Search Results

1

Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis.

Hill JW, Xu Y, Preitner F, Fukuda M, Cho YR, Luo J, Balthasar N, Coppari R, Cantley LC, Kahn BB, Zhao JJ, Elmquist JK. Hill JW, et al. Among authors: luo j. Endocrinology. 2009 Nov;150(11):4874-82. doi: 10.1210/en.2009-0454. Epub 2009 Oct 9. Endocrinology. 2009. PMID: 19819947 Free PMC article.

2

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.

Hill JW, Williams KW, Ye C, Luo J, Balthasar N, Coppari R, Cowley MA, Cantley LC, Lowell BB, Elmquist JK. Hill JW, et al. Among authors: luo j. J Clin Invest. 2008 May;118(5):1796-805. doi: 10.1172/JCI32964. J Clin Invest. 2008. PMID: 18382766 Free PMC article.

3

The negative regulation of phosphoinositide 3-kinase signaling by p85 and it's implication in cancer.

Luo J, Cantley LC. Luo J, et al. Cell Cycle. 2005 Oct;4(10):1309-12. doi: 10.4161/cc.4.10.2062. Epub 2005 Oct 28. Cell Cycle. 2005. PMID: 16131837

4

The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex.

Luo J, Field SJ, Lee JY, Engelman JA, Cantley LC. Luo J, et al. J Cell Biol. 2005 Aug 1;170(3):455-64. doi: 10.1083/jcb.200503088. Epub 2005 Jul 25. J Cell Biol. 2005. PMID: 16043515 Free PMC article.

5

Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.

Taniguchi CM, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley LC, Kahn CR. Taniguchi CM, et al. Among authors: luo j. Cell Metab. 2006 May;3(5):343-53. doi: 10.1016/j.cmet.2006.04.005. Cell Metab. 2006. PMID: 16679292 Free article.

6

Loss of class IA PI3K signaling in muscle leads to impaired muscle growth, insulin response, and hyperlipidemia.

Luo J, Sobkiw CL, Hirshman MF, Logsdon MN, Li TQ, Goodyear LJ, Cantley LC. Luo J, et al. Cell Metab. 2006 May;3(5):355-66. doi: 10.1016/j.cmet.2006.04.003. Cell Metab. 2006. PMID: 16679293 Free article.

7

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism.

Engelman JA, Luo J, Cantley LC. Engelman JA, et al. Among authors: luo j. Nat Rev Genet. 2006 Aug;7(8):606-19. doi: 10.1038/nrg1879. Nat Rev Genet. 2006. PMID: 16847462 Review.

8

Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN.

Taniguchi CM, Tran TT, Kondo T, Luo J, Ueki K, Cantley LC, Kahn CR. Taniguchi CM, et al. Among authors: luo j. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12093-7. doi: 10.1073/pnas.0604628103. Epub 2006 Jul 31. Proc Natl Acad Sci U S A. 2006. PMID: 16880400 Free PMC article.

9

Targeting the PI3K-Akt pathway in human cancer: rationale and promise.

Luo J, Manning BD, Cantley LC. Luo J, et al. Cancer Cell. 2003 Oct;4(4):257-62. doi: 10.1016/s1535-6108(03)00248-4. Cancer Cell. 2003. PMID: 14585353 Free article. Review. No abstract available.

10

The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.

Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Alemán JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR. Taniguchi CM, et al. Among authors: luo j. Cancer Res. 2010 Jul 1;70(13):5305-15. doi: 10.1158/0008-5472.CAN-09-3399. Epub 2010 Jun 8. Cancer Res. 2010. PMID: 20530665 Free PMC article.

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