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Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.
Lamkanfi M, Mueller JL, Vitari AC, Misaghi S, Fedorova A, Deshayes K, Lee WP, Hoffman HM, Dixit VM. Lamkanfi M, et al. Among authors: lee wp. J Cell Biol. 2009 Oct 5;187(1):61-70. doi: 10.1083/jcb.200903124. J Cell Biol. 2009. PMID: 19805629 Free PMC article.
TWEAK attenuates the transition from innate to adaptive immunity.
Maecker H, Varfolomeev E, Kischkel F, Lawrence D, LeBlanc H, Lee W, Hurst S, Danilenko D, Li J, Filvaroff E, Yang B, Daniel D, Ashkenazi A. Maecker H, et al. Cell. 2005 Dec 2;123(5):931-44. doi: 10.1016/j.cell.2005.09.022. Cell. 2005. PMID: 16325585 Free article.
Cryopyrin activates the inflammasome in response to toxins and ATP.
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, Lee WP, Weinrauch Y, Monack DM, Dixit VM. Mariathasan S, et al. Among authors: lee wp. Nature. 2006 Mar 9;440(7081):228-32. doi: 10.1038/nature04515. Epub 2006 Jan 11. Nature. 2006. PMID: 16407890
Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells.
Misaghi S, Garris CS, Sun Y, Nguyen A, Zhang J, Sebrell A, Senger K, Yan D, Lorenzo MN, Heldens S, Lee WP, Xu M, Wu J, DeForge L, Sai T, Dixit VM, Zarrin AA. Misaghi S, et al. Among authors: lee wp. J Immunol. 2010 Jul 1;185(1):166-73. doi: 10.4049/jimmunol.1000515. Epub 2010 May 28. J Immunol. 2010. PMID: 20511552
Non-canonical inflammasome activation targets caspase-11.
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, Newton K, Qu Y, Liu J, Heldens S, Zhang J, Lee WP, Roose-Girma M, Dixit VM. Kayagaki N, et al. Among authors: lee wp. Nature. 2011 Oct 16;479(7371):117-21. doi: 10.1038/nature10558. Nature. 2011. PMID: 22002608
562 results