Kucera GL - Search Results

1

Gold(I) analogues of a platinum-acridine antitumor agent are only moderately cytotoxic but show potent activity against Mycobacterium tuberculosis.

Eiter LC, Hall NW, Day CS, Saluta G, Kucera GL, Bierbach U. Eiter LC, et al. Among authors: kucera gl. J Med Chem. 2009 Nov 12;52(21):6519-22. doi: 10.1021/jm9012856. J Med Chem. 2009. PMID: 19803526 Free PMC article.

2

Role of c-Jun N-terminal kinase/p38 stress signaling in 1-beta-D-arabinofuranosylcytosine-induced apoptosis.

Stadheim TA, Saluta GR, Kucera GL. Stadheim TA, et al. Among authors: kucera gl. Biochem Pharmacol. 2000 Feb 15;59(4):407-18. doi: 10.1016/s0006-2952(99)00330-5. Biochem Pharmacol. 2000. PMID: 10644049

3

Design, synthesis, and biological activity of a novel non-cisplatin-type platinum-acridine pharmacophore.

Martins ET, Baruah H, Kramarczyk J, Saluta G, Day CS, Kucera GL, Bierbach U. Martins ET, et al. Among authors: kucera gl. J Med Chem. 2001 Dec 6;44(25):4492-6. doi: 10.1021/jm010293m. J Med Chem. 2001. PMID: 11728195

4

Copper-nuclease efficiency correlates with cytotoxicity for the 4-methoxypyrrolic natural products.

Melvin MS, Wooton KE, Rich CC, Saluta GR, Kucera GL, Lindquist N, Manderville RA. Melvin MS, et al. Among authors: kucera gl. J Inorg Biochem. 2001 Dec 1;87(3):129-35. doi: 10.1016/s0162-0134(01)00338-5. J Inorg Biochem. 2001. PMID: 11730894

5

Influence of the a-ring on the proton affinity and anticancer properties of the prodigiosins.

Melvin MS, Tomlinson JT, Park G, Day CS, Saluta GR, Kucera GL, Manderville RA. Melvin MS, et al. Among authors: kucera gl. Chem Res Toxicol. 2002 May;15(5):734-41. doi: 10.1021/tx025507x. Chem Res Toxicol. 2002. PMID: 12018996

6

Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate.

Barry CG, Turney EC, Day CS, Saluta G, Kucera GL, Bierbach U. Barry CG, et al. Among authors: kucera gl. Inorg Chem. 2002 Dec 30;41(26):7159-69. doi: 10.1021/ic025744n. Inorg Chem. 2002. PMID: 12495358

7

Synthesis and cytotoxic activity of two novel 1-dodecylthio-2-decyloxypropyl-3-phosphatidic acid conjugates with gemcitabine and cytosine arabinoside.

Alexander RL, Morris-Natschke SL, Ishaq KS, Fleming RA, Kucera GL. Alexander RL, et al. Among authors: kucera gl. J Med Chem. 2003 Sep 11;46(19):4205-8. doi: 10.1021/jm020571x. J Med Chem. 2003. PMID: 12954073

8

Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine.

Guddneppanavar R, Saluta G, Kucera GL, Bierbach U. Guddneppanavar R, et al. Among authors: kucera gl. J Med Chem. 2006 Jun 1;49(11):3204-14. doi: 10.1021/jm060035v. J Med Chem. 2006. PMID: 16722638

9

Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity.

Guddneppanavar R, Choudhury JR, Kheradi AR, Steen BD, Saluta G, Kucera GL, Day CS, Bierbach U. Guddneppanavar R, et al. Among authors: kucera gl. J Med Chem. 2007 May 3;50(9):2259-63. doi: 10.1021/jm0614376. Epub 2007 Apr 5. J Med Chem. 2007. PMID: 17408248

10

Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: effect of metal cis/trans isomerism and DNA threading groups.

Choudhury JR, Guddneppanavar R, Saluta G, Kucera GL, Bierbach U. Choudhury JR, et al. Among authors: kucera gl. J Med Chem. 2008 Jun 12;51(11):3069-72. doi: 10.1021/jm8003569. Epub 2008 May 6. J Med Chem. 2008. PMID: 18457380 Free PMC article.

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