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Page 1
N,N-Diethyl-4-[(3-hydroxyphenyl)(piperidin-4-yl)amino] benzamide derivatives: the development of diaryl amino piperidines as potent delta opioid receptor agonists with in vivo anti-nociceptive activity in rodent models.
Jones P, Griffin AM, Gawell L, Lavoie R, Delorme D, Roberts E, Brown W, Walpole C, Xiao W, Boulet J, Labarre M, Coupal M, Butterworth J, St-Onge S, Hodzic L, Salois D. Jones P, et al. Among authors: labarre m. Bioorg Med Chem Lett. 2009 Nov 1;19(21):5994-8. doi: 10.1016/j.bmcl.2009.09.072. Epub 2009 Sep 22. Bioorg Med Chem Lett. 2009. PMID: 19800791
New diarylmethylpiperazines as potent and selective nonpeptidic delta opioid receptor agonists with increased In vitro metabolic stability.
Plobeck N, Delorme D, Wei ZY, Yang H, Zhou F, Schwarz P, Gawell L, Gagnon H, Pelcman B, Schmidt R, Yue SY, Walpole C, Brown W, Zhou E, Labarre M, Payza K, St-Onge S, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Plobeck N, et al. Among authors: labarre m. J Med Chem. 2000 Oct 19;43(21):3878-94. doi: 10.1021/jm000228x. J Med Chem. 2000. PMID: 11052793
N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues.
Wei ZY, Brown W, Takasaki B, Plobeck N, Delorme D, Zhou F, Yang H, Jones P, Gawell L, Gagnon H, Schmidt R, Yue SY, Walpole C, Payza K, St-Onge S, Labarre M, Godbout C, Jakob A, Butterworth J, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Wei ZY, et al. Among authors: labarre m. J Med Chem. 2000 Oct 19;43(21):3895-905. doi: 10.1021/jm000229p. J Med Chem. 2000. PMID: 11052794
Potent and orally efficacious benzothiazole amides as TRPV1 antagonists.
Besidski Y, Brown W, Bylund J, Dabrowski M, Dautrey S, Harter M, Horoszok L, Hu Y, Johnson D, Johnstone S, Jones P, Leclerc S, Kolmodin K, Kers I, Labarre M, Labrecque D, Laird J, Lundström T, Martino J, Maudet M, Munro A, Nylöf M, Penwell A, Rotticci D, Slaitas A, Sundgren-Andersson A, Svensson M, Terp G, Villanueva H, Walpole C, Zemribo R, Griffin AM. Besidski Y, et al. Among authors: labarre m. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6205-11. doi: 10.1016/j.bmcl.2012.08.018. Epub 2012 Aug 14. Bioorg Med Chem Lett. 2012. PMID: 22939234
Inverse agonism by Dmt-Tic analogues and HS 378, a naltrindole analogue.
Labarre M, Butterworth J, St-Onge S, Payza K, Schmidhammer H, Salvadori S, Balboni G, Guerrini R, Bryant SD, Lazarus LH. Labarre M, et al. Eur J Pharmacol. 2000 Oct 6;406(1):R1-3. doi: 10.1016/s0014-2999(00)00636-1. Eur J Pharmacol. 2000. PMID: 11011049
Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs.
Lembo PM, Grazzini E, Groblewski T, O'Donnell D, Roy MO, Zhang J, Hoffert C, Cao J, Schmidt R, Pelletier M, Labarre M, Gosselin M, Fortin Y, Banville D, Shen SH, Ström P, Payza K, Dray A, Walker P, Ahmad S. Lembo PM, et al. Among authors: labarre m. Nat Neurosci. 2002 Mar;5(3):201-9. doi: 10.1038/nn815. Nat Neurosci. 2002. PMID: 11850634
50 results