Zhang X - Search Results

1

Inhibition of CYP3A by erythromycin: in vitro-in vivo correlation in rats.

Zhang X, Galinsky RE, Kimura RE, Quinney SK, Jones DR, Hall SD. Zhang X, et al. Drug Metab Dispos. 2010 Jan;38(1):61-72. doi: 10.1124/dmd.109.028290. Drug Metab Dispos. 2010. PMID: 19797607

2

Prediction of the effect of erythromycin, diltiazem, and their metabolites, alone and in combination, on CYP3A4 inhibition.

Zhang X, Jones DR, Hall SD. Zhang X, et al. Drug Metab Dispos. 2009 Jan;37(1):150-60. doi: 10.1124/dmd.108.022178. Epub 2008 Oct 14. Drug Metab Dispos. 2009. PMID: 18854379

3

Semiphysiologically based pharmacokinetic models for the inhibition of midazolam clearance by diltiazem and its major metabolite.

Zhang X, Quinney SK, Gorski JC, Jones DR, Hall SD. Zhang X, et al. Drug Metab Dispos. 2009 Aug;37(8):1587-97. doi: 10.1124/dmd.109.026658. Epub 2009 May 6. Drug Metab Dispos. 2009. PMID: 19420129 Clinical Trial.

4

Physiologically based pharmacokinetic model of mechanism-based inhibition of CYP3A by clarithromycin.

Quinney SK, Zhang X, Lucksiri A, Gorski JC, Li L, Hall SD. Quinney SK, et al. Among authors: zhang x. Drug Metab Dispos. 2010 Feb;38(2):241-8. doi: 10.1124/dmd.109.028746. Epub 2009 Nov 2. Drug Metab Dispos. 2010. PMID: 19884323 Free PMC article.

5

Occupancy of Nociceptin/Orphanin FQ Peptide Receptors by the Antagonist LY2940094 in Rats and Healthy Human Subjects.

Raddad E, Chappell A, Meyer J, Wilson A, Ruegg CE, Tauscher J, Statnick MA, Barth V, Zhang X, Verfaille SJ. Raddad E, et al. Among authors: zhang x. Drug Metab Dispos. 2016 Sep;44(9):1536-42. doi: 10.1124/dmd.116.070359. Epub 2016 Jun 27. Drug Metab Dispos. 2016. PMID: 27353045

6

Prediction of Transporter-Mediated Drug-Drug Interactions for Baricitinib.

Posada MM, Cannady EA, Payne CD, Zhang X, Bacon JA, Pak YA, Higgins JW, Shahri N, Hall SD, Hillgren KM. Posada MM, et al. Among authors: zhang x. Clin Transl Sci. 2017 Nov;10(6):509-519. doi: 10.1111/cts.12486. Epub 2017 Jul 27. Clin Transl Sci. 2017. PMID: 28749581 Free PMC article. Clinical Trial.

7

Gatifloxacin pharmacokinetics in healthy men and women.

Zhang X, Overholser BR, Kays MB, Sowinski KM. Zhang X, et al. J Clin Pharmacol. 2006 Oct;46(10):1154-62. doi: 10.1177/0091270006291840. J Clin Pharmacol. 2006. PMID: 16988204 Clinical Trial.

8

Pharmacokinetics, Safety, and Tolerability of Single- and Multiple-Dose Once-Daily Baricitinib in Healthy Chinese Subjects: A Randomized Placebo-Controlled Study.

Zhao X, Sheng XY, Payne CD, Zhang X, Wang F, Cui YM. Zhao X, et al. Among authors: zhang x. Clin Pharmacol Drug Dev. 2020 Nov;9(8):952-960. doi: 10.1002/cpdd.868. Epub 2020 Sep 17. Clin Pharmacol Drug Dev. 2020. PMID: 32945153 Free PMC article. Clinical Trial.

9

Dose selection using a semi-mechanistic integrated glucose-insulin-glucagon model: designing phase 2 trials for a novel oral glucokinase activator.

Zhang X, Schneck K, Bue-Valleskey J, Yeo KP, Heathman M, Sinha V. Zhang X, et al. J Pharmacokinet Pharmacodyn. 2013 Feb;40(1):53-65. doi: 10.1007/s10928-012-9286-9. Epub 2012 Dec 22. J Pharmacokinet Pharmacodyn. 2013. PMID: 23263772 Clinical Trial.

10

Dose/Exposure-Response Modeling to Support Dosing Recommendation for Phase III Development of Baricitinib in Patients with Rheumatoid Arthritis.

Zhang X, Chua L, Ernest C 2nd, Macias W, Rooney T, Tham LS. Zhang X, et al. CPT Pharmacometrics Syst Pharmacol. 2017 Dec;6(12):804-813. doi: 10.1002/psp4.12251. Epub 2017 Oct 17. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28891251 Free PMC article. Clinical Trial.

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