Sears DD - Search Results

1

12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.

Sears DD, Miles PD, Chapman J, Ofrecio JM, Almazan F, Thapar D, Miller YI. Sears DD, et al. PLoS One. 2009 Sep 29;4(9):e7250. doi: 10.1371/journal.pone.0007250. PLoS One. 2009. PMID: 19787041 Free PMC article.

2

Selective modulation of promoter recruitment and transcriptional activity of PPARgamma.

Sears DD, Hsiao A, Ofrecio JM, Chapman J, He W, Olefsky JM. Sears DD, et al. Biochem Biophys Res Commun. 2007 Dec 21;364(3):515-21. doi: 10.1016/j.bbrc.2007.10.057. Epub 2007 Oct 18. Biochem Biophys Res Commun. 2007. PMID: 17963725 Free PMC article.

3

Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization.

Sears DD, Hsiao G, Hsiao A, Yu JG, Courtney CH, Ofrecio JM, Chapman J, Subramaniam S. Sears DD, et al. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18745-50. doi: 10.1073/pnas.0903032106. Epub 2009 Oct 19. Proc Natl Acad Sci U S A. 2009. PMID: 19841271 Free PMC article. Clinical Trial.

4

Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice.

Li P, Lu M, Nguyen MTA, Bae EJ, Chapman J, Feng D, Hawkins M, Pessin JE, Sears DD, Nguyen AK, Amidi A, Watkins SM, Nguyen U, Olefsky JM. Li P, et al. Among authors: sears dd. J Biol Chem. 2010 May 14;285(20):15333-15345. doi: 10.1074/jbc.M110.100263. Epub 2010 Mar 22. J Biol Chem. 2010. PMID: 20308074 Free PMC article.

5

Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats.

Hsiao G, Chapman J, Ofrecio JM, Wilkes J, Resnik JL, Thapar D, Subramaniam S, Sears DD. Hsiao G, et al. Among authors: sears dd. Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E164-74. doi: 10.1152/ajpendo.00219.2010. Epub 2010 Oct 19. Am J Physiol Endocrinol Metab. 2011. PMID: 20959535 Free PMC article.

6

Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice.

Chapman J, Miles PD, Ofrecio JM, Neels JG, Yu JG, Resnik JL, Wilkes J, Talukdar S, Thapar D, Johnson K, Sears DD. Chapman J, et al. Among authors: sears dd. PLoS One. 2010 Nov 12;5(11):e13959. doi: 10.1371/journal.pone.0013959. PLoS One. 2010. PMID: 21103061 Free PMC article.

7

Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity.

Li P, Fan W, Xu J, Lu M, Yamamoto H, Auwerx J, Sears DD, Talukdar S, Oh D, Chen A, Bandyopadhyay G, Scadeng M, Ofrecio JM, Nalbandian S, Olefsky JM. Li P, et al. Among authors: sears dd. Cell. 2011 Nov 11;147(4):815-26. doi: 10.1016/j.cell.2011.09.050. Cell. 2011. PMID: 22078880 Free PMC article.

8

Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.

Lazic M, Inzaugarat ME, Povero D, Zhao IC, Chen M, Nalbandian M, Miller YI, Cherñavsky AC, Feldstein AE, Sears DD. Lazic M, et al. Among authors: sears dd. PLoS One. 2014 Sep 24;9(9):e107658. doi: 10.1371/journal.pone.0107658. eCollection 2014. PLoS One. 2014. PMID: 25251155 Free PMC article.

9

Frequency and Circadian Timing of Eating May Influence Biomarkers of Inflammation and Insulin Resistance Associated with Breast Cancer Risk.

Marinac CR, Sears DD, Natarajan L, Gallo LC, Breen CI, Patterson RE. Marinac CR, et al. Among authors: sears dd. PLoS One. 2015 Aug 25;10(8):e0136240. doi: 10.1371/journal.pone.0136240. eCollection 2015. PLoS One. 2015. PMID: 26305095 Free PMC article.

10

AIBP protects against metabolic abnormalities and atherosclerosis.

Schneider DA, Choi SH, Agatisa-Boyle C, Zhu L, Kim J, Pattison J, Sears DD, Gordts PLSM, Fang L, Miller YI. Schneider DA, et al. Among authors: sears dd. J Lipid Res. 2018 May;59(5):854-863. doi: 10.1194/jlr.M083618. Epub 2018 Mar 20. J Lipid Res. 2018. PMID: 29559522 Free PMC article.

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